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      Experimental Study and Modelling of Ultrafine Particles Formation by Using the Supercritical Fluids

      , Ph.D. Dissertation Sharif University of Technology Karimi Sabet, Javad (Author) ; Gotbi, Cyrus (Supervisor) ; Khanchi, AliReza (Supervisor) ; Farhadpour, Farhad (Co-Advisor) ; Dorkoosh, Farid (Co-Advisor)
      Abstract
      In this research, we focused on demonstration of features and advantages of supercritical fluids technology to formation of fine particles (nano and micro scales) from bulk materials (solid) and synthesized metal oxides nanoparticles. Therefore, using two different fluids, carbon dioxide and water, and two completely different methods, the Rapid expansion of supercritical solution and supercritical hydrothermal, were used to produce fine particles of drug (acetaminophen) and nano metal oxide (zirconium dioxide and bismuth ferrite). The summary of this research are as follows:1. The solubility of acetaminophen in SuperCritical-Carbon Dioxide (SC-CO2) with and without menthol as a cosolvent... 
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