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farokhi--mehdi
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Synthesis and Characterization of a Novel Hydrogel Wound Dressing based on Silk Fibroin and Zinc Oxide Nanoparticles
, M.Sc. Thesis Sharif University of Technology ; Nemati, Ali (Supervisor) ; Shokrgozar, Mohammad Ali (Supervisor) ; Farokhi, Mehdi (Co-Supervisor)
Abstract
Recently, some wound dressings have been designed that are expected to enhance the wound healing process and prevent blood bleeding and infection. Polymeric dressings have attracted attention due to their biocompatibility, biodegradability, lack of toxicity, and non-allergenic nature. There is widespread interest in using silk fibroin (SF) for this purpose because of its unique properties. Given these points, we have designed an injectable antioxidant hydrogel wound dressing based on SF and Polydopamine(PDA) modified ZnO nanoparticles. First, ZnO nanoparticles were doped with Cu and then modified with PDA (ZnCuO@PDA). XRD, FTIR, SEM, and TEM characterizations were carried out to confirm the...