Search for: ghalkhani--m
Total 24 records
Nano composite coating based on cellulose nanofibers/carbon nanoparticles: application to voltammetric determination of clonazepam, Article Journal of Solid State Electrochemistry ; Vol. 19, issue. 1 , 2014 , p. 251-260 ; Balotf, H ; Ghalkhani, M ; Sharif University of Technology
A novel electrochemical sensor for clonazepam (CLNP) was fabricated based on immobilizing cellulose nanofibers/carbon nanoparticles (CNFs/CNPs) nanocomposite on glassy carbon electrode (CNFs/CNPs/GCE). The combination of CNFs and CNPs produced a novel kind of structurally uniform and electro-analytically active nanocomposite. The surface morphology of CNFs/CNPs layer deposited onto glassy carbon electrode was characterized by scanning electron microscopy. The results of the voltammetric investigations showed a considerable enhancement in the cathodic peak current of CLNP (up to 60 times) on the surface of CNFs/CNPs/GCE relative to the bare GCE. Under the optimal conditions, the modified...
Electrochemistry of levo-thyroxin on edge-plane pyrolytic graphite electrode: application to sensitive analytical determinations, Article Electroanalysis ; Volume 23, Issue 8 , JUL , 2011 , Pages 1875-1880 ; 10400397 (ISSN) ; Shahrokhian, S ; Ghalkhani, M ; Sharif University of Technology
The electrochemical response of sodium levo-thyroxin (T4) at the surface of an edge plane pyrolytic graphite (EPPG) electrode is investigated using cyclic voltammetric technique in the presence of 0.1M HCl as supporting electrolyte. T4 underwent totally irreversible oxidation at this system and a well-defined peak at 821mV was obtained. Compared to the signals obtained in the optimized conditions at bare glassy carbon and carbon paste electrodes, the oxidation current of T4 at an EPPG electrode was greatly enhanced. The electrochemical process of T4 was explored and the experimental conditions were optimized. The oxidation peak current represented a linear dependence on T4 concentration from...
Nanocellulose/Carbon Nanoparticles Nanocomposite Film Modified Electrode for Durable and Sensitive Electrochemical Determination of Metoclopramide, Article Electroanalysis ; Volume 27, Issue 11 , November , 2015 , Pages 2637-2644 ; 10400397 (ISSN) ; Naderi, L ; Ghalkhani, M ; Sharif University of Technology
Wiley-VCH Verlag 2015
A novel electrochemical sensor based on nanocellulose-carbon nanoparticles (NC-CNPs) nanocomposite film modified glassy carbon electrode (GCE) is developed for the analysis of metoclopramide (MCP). Atomic force microscopy, scanning electron microscopy and electrochemical impedance spectroscopy were used to characterize the roughness, surface morphology and performance of the deposited modifier film on GCE. SEM image demonstrated that modifier nanoparticles are uniformly deposited on GCE, with an average size of less than 50nm. The electrochemical behavior of MCP and its oxidation product is studied using linear sweep and cyclic voltammetry over a wide pH range on NC-CNPs modified glassy...
Electrochemical determination of piroxicam on the surface of pyrolytic graphite electrode modified with a film of carbon nanoparticle-chitosan, Article Microchimica Acta ; Volume 170, Issue 1 , August , 2010 , Pages 141-146 ; 00263672 (ISSN) ; Jokar, E ; Ghalkhani, M ; Sharif University of Technology
The electrochemical behavior of the anti-inflammatory drug piroxicam is studied at the surface of a plain pyrolytic graphite electrode modified with chitosan-doped carbon nanoparticles. An electroactive surface was produced by drop-casting a suspension of the modifier and characterized by atomic force microscopy. A remarkable enhancement is found in studies on the cyclic voltammetric response towards piroxicam. This is described on the basis of the thin-layer mass transport regimes within the porous films, which leads to a considerable increase in the active surface area of the electrode. The electrode shows a linear response to piroxicam in the range of 0.05-50 μM, with a detection limit of...
Glassy carbon electrodes modified with a film of nanodiamond-graphite/chitosan: Application to the highly sensitive electrochemical determination of Azathioprine, Article Electrochimica Acta ; Volume 55, Issue 11 , 2010 , Pages 3621-3627 ; 00134686 (ISSN) ; Ghalkhani, M ; Sharif University of Technology
A novel modified glassy carbon electrode with a film of nanodiamond-graphite/chitosan is constructed and used for the sensitive voltammetric determination of azathioprine (Aza). The surface morphology and thickness of the film modifier are characterized using atomic force microscopy. The electrochemical response characteristics of the electrode toward Aza are investigated by means of cyclic voltammetry. The modified electrode showed an efficient catalytic role for the electrochemical reduction of Aza, leading to a remarkable decrease in reduction overpotential and enhancement of the kinetics of the electrode reaction with a significant increase of peak current. The effects of experimental...
Modification of the electrode surface by ag nanoparticles decorated nano diamond-graphite for voltammetric determination of ceftizoxime, Article Electroanalysis ; Volume 28, Issue 3 , 2016 , Pages 469-476 ; 10400397 (ISSN) ; Ranjbar, S ; Ghalkhani, M ; Sharif University of Technology
Wiley-VCH Verlag 2016
A modified glassy carbon electrode with a film of nano diamond-graphite nano mixture decorated with Ag nanoparticles (AgNPs-NDG/GCE) was constructed and used for sensitive voltammetric determination of ceftizoxime (CFX). Morphology of AgNPs-NDG/GCE has been examined by scanning electron microscopy (SEM) and atomic force microscopy (AFM). Experimental variables such as deposited amount of the modifier suspension, pH of the supporting electrolyte and accumulation potential and time were optimized by monitoring of CV and LSV responses of CFX. The results illustrate that AgNPs-NDG/GCE exhibits an excellent electrocatalytic effect in the electro-oxidation of CFX that leads to a considerable...
Modified glassy carbon electrodes based on carbon nanostructures for ultrasensitive electrochemical determination of furazolidone, Article Materials Science and Engineering C ; Volume 61 , 2016 , Pages 842-850 ; 09284931 (ISSN) ; Naderi, L ; Ghalkhani, M ; Sharif University of Technology
The electrochemical behavior of Furazolidone (Fu) was investigated on the surface of the glassy carbon electrode modified with different carbon nanomaterials, including carbon nanotubes (CNTs), carbon nanoparticles (CNPs), nanodiamond-graphite (NDG), graphene oxide (GO), reduced graphene oxide (RGO) and RGO-CNT hybrids (various ratios) using linear sweep voltammetry (LSV). The results of voltammetric studies exhibited a considerable increase in the cathodic peak current of Fu at the RGO modified GCE, compared to other modified electrodes and also bare GCE. The surface morphology and nature of the RGO film was thoroughly characterized by scanning electron microscopy (SEM), atomic force...
Article Electrochemistry Communications ; Volume 11, Issue 7 , 2009 , Pages 1425-1428 ; 13882481 (ISSN) ; Ghalkhani, M ; Sharif University of Technology
Thin carbon nanoparticle/Nafion film (CNP/N), as a novel electrode material, is formed on the surface of the glassy carbon electrode in a simple solvent evaporation process. The electrochemical behavior of Azathioprine (Aza) at the CNP/N-modified electrode is investigated in detail by the means of cyclic voltammetry. During the electrochemical reduction of Aza, an irreversible cathodic peak is appeared. Cyclic voltammetric studies indicated that the reduction process has an irreversible and adsorption-like behavior. The observed reduction peak is attributed to a four-electron process referring to the reduction of nitro group to the corresponding hydroxylamine. The prepared electrode showed...
Article Sensors and Actuators, B: Chemical ; Volume 293 , 2019 , Pages 183-209 ; 09254005 (ISSN) ; Ghalkhani, M ; Shahrokhian, S ; Sharif University of Technology
Elsevier B.V 2019
The emergence of nanoscience and nanotechnology has opened up new horizons to researchers. In this regard, carbon nanomaterials are considered as the cornerstone of numerous investigations. Among various carbon nanostructures, “Carbon nanoparticles (CNPs)” have attracted a great deal of attention during the past few years due to their unique properties such as high surface area, non-toxicity, biocompatibility as well as simple and low-cost synthetic procedures via environmentally friendly routes. Thanks to these properties along with their interesting optical behavior, CNPs have found diverse applications in the fields of bioimaging, nanomedicine, photo/electro-catalysis, and bio/chemical...
Simultaneous voltammetric detection of ascorbic acid and uric acid at a carbon-paste modified electrode incorporating thionine-nafion ion-pair as an electron mediator, Article Electrochimica Acta ; Volume 51, Issue 13 , 2006 , Pages 2599-2606 ; 00134686 (ISSN) ; Ghalkhani, M ; Sharif University of Technology
The electrochemical behavior of ascorbic acid (AA) and uric acid (UA) at the surface of a carbon-paste electrode modified with incorporate thionine-nafion ion-paired was thoroughly investigated. The results show the presence of nafion inside the matrix of modified electrode, because of the effective ion-pairing and hydrophobic interactions, significantly enhances the stability of thionine as an electron mediator inside the modified electrode. A high reproducibility in voltammetric response to analyte species results because of this enhancement. The cyclic voltammetric studies using the prepared modified electrode show the best electrocatalytic property for the electro-oxidation of AA and...
Modification of well-aligned carbon nanotubes with dihexadecyl hydrogen phosphate: Application to highly sensitive nanomolar detection of simvastatin, Article Journal of Applied Electrochemistry ; Volume 44, Issue 2 , February , 2014 , Pages 263-277 ; ISSN: 0021891X ; Afshar, A ; Dolati, A ; Ghalkhani, M ; Sharif University of Technology
The first usage of dihexadecyl hydrogen phosphate (DHP)-modified highly oriented multi-walled carbon nanotube (MWCNTs) forests in a sensor configuration was developed to investigate the electrochemical oxidation and determination of simvastatin (SV) in pharmaceutical dosage forms. Synthesis of well-aligned MWCNTs on a conductive Ta substrate by catalytic vapor deposition technique using a common chemical, ethylenediamine, and without being plasma-aided was reported. The electrochemical behavior and oxidation of SV at the aligned MWCNTs/DHP/Ta electrode were discussed in detail through cyclic voltammetry and differential pulse voltammetry. This modified electrode showed considerably higher...
Construction of Pt nanoparticle-decorated graphene nanosheets and carbon nanospheres nanocomposite-modified electrodes: Application to ultrasensitive electrochemical determination of cefepime, Article RSC Advances ; Volume 4, Issue 15 , 2014 , Pages 7786-7794 ; ISSN: 20462069 ; Hosseini Nassab, N ; Ghalkhani, M ; Sharif University of Technology
A novel ultrasensitive modified electrode was fabricated with a graphene nanosheets and carbon nanospheres (GNS-CNS)-based nanocomposite film as a powerful platform. Pt nanoparticles (PtNPs) were simply electrodeposited onto the GNS-CNS-coated glassy carbon electrode creating a PtNPs/GNS-CNS hybrid nanocomposite modified electrode. Scanning electron microscopy, energy dispersive X-ray spectroscopy and linear sweep voltammetry (LSV) techniques were used for the characterization of the prepared modified electrode. The results of investigation of electrochemical response characteristics of cefepime (CP) revealed a considerable improvement in the oxidation peak current of CP on PtNPs/GNS-CNS/GCE...
Application of glassy carbon electrode modified with a carbon nanoparticle/melamine thin film for voltammetric determination of raloxifene, Article Journal of Electroanalytical Chemistry ; Volume 780 , 2016 , Pages 126-133 ; 15726657 (ISSN) ; Ghalkhani, M ; Balotf, H ; Salimian, R ; Sharif University of Technology
Elsevier B.V 2016
As a selective estrogen receptor modulator, raloxifene (RXF) prevent of osteoporosis in postmenopausal women by estrogenic actions on bone and decreases the risk of invasive breast cancer by anti-estrogenic actions on the breast and uterus tissue. However, RXF may increase the risk of blood clots, including deep vein thrombosis and pulmonary embolism. For the first time glassy carbon electrode modified with a thin film of melamine/carbon nanoparticles (CNPs/Mela) was constructed and used for the sensitive voltammetric determination of RXF. In comparison with unmodified electrode, the presence of the CNPs/Mela film resulted in a remarkable increase in the peak currents and sharpness of the...
Biomimetic sensor for dobutamine employing Nano- TiO2/Nafion/carbon nanoparticles modified electrode, Article Electroanalysis ; Volume 28, Issue 5 , 2016 , Pages 970-978 ; 10400397 (ISSN) ; Ghalkhani, M ; Kohansal, R ; Mohammadi, R ; Sharif University of Technology
Wiley-VCH Verlag 2016
A novel voltammetric biosensor based on nano-TiO2/nafion/carbon nanoparticles modified glassy carbon electrode (TiO2/N/CNP/GCE) was developed for the determination of dobutamine (DBA). Characterization of the surface morphology and property of TiO2/N/CNP layer was carried out by the scanning electron microscopy and atomic force microscopy. The electrochemical performance of the modified electrode was investigated by means of the cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy techniques. Effective experimental variables, such as the scan rate, pH of the supporting electrolyte, drop size of the casted modifier suspension and accumulation...
Application of 3D gold nanotube ensembles in electrochemical sensing of ultra-trace Hg (II) in drinkable water, Article Surfaces and Interfaces ; Volume 10 , 2018 , Pages 27-31 ; 24680230 (ISSN) ; Ghorbani, M ; Dolati, A ; Ghalkhani, M ; Sharif University of Technology
Elsevier B.V 2018
As a novel and highly sensitive sensor, three-dimensional gold nanoelectrode ensembles (3D GNE) prepared by gold deposition inside the parallel pores of a porous template have been successfully applied in electrochemical determination experiments. In this study, we report on the fabrication of 3D gold nanotubes (GNT) and their application in determination of Hg (II) in water. The morphology and crystal structure of the 3D GNT were characterized by field emission scanning electron microscope (FE-SEM) and X-ray diffraction (XRD), respectively. The sensitivity of the fabricated electrode towards Hg (II) was examined using anodic stripping voltammetry (ASV) as a powerful technique in...
Application of carbon-paste electrode modified with iron phthalocyanine for voltammetric determination of epinephrine in the presence of ascorbic acid and uric acid, Article Sensors and Actuators, B: Chemical ; Volume 137, Issue 2 , 2009 , Pages 669-675 ; 09254005 (ISSN) ; Ghalkhani, M ; Amini, M. K ; Sharif University of Technology
A carbon-paste electrode (CPE) modified with iron(II) phthalocyanine was used for the sensitive voltammetric determination of epinephrine (EN). The electrochemical response characteristics of the modified electrode toward EN, ascorbic acid (AA) and uric acid (UA) were investigated by cyclic and differential pulse voltammetry (CV and DPV). The results show an efficient catalytic activity of the electrode for the electro-oxidation of EN, which leads to improvement of reversibility of the electrode response and lowering its overpotential by more than 100 mV. The effect of pH and potential sweep rate on the mechanism of the electrode process was investigated. The modified electrode exhibits an...
Highly sensitive 3D gold nanotube ensembles: Application to electrochemical determination of metronidazole, Article Electrochimica Acta ; Volume 106 , 2013 , Pages 288-292 ; 00134686 (ISSN) ; Ghorbani, M ; Ghalkhani, M ; Vossoughi, M ; Dolati, A ; Sharif University of Technology
Three-dimensional gold nanoelectrode ensembles (3D GNE) have proven to be promising nanoelectrodes by representing much higher sensitivity compared to both their 2D nanostructures and bulk counterparts. The sensitivity of 3D gold nanotubes (GNTs) fabricated through electrodeposition inside the pores of polycarbonate templates, was examined toward metronidazole (MTZ) as one of their pharmaceutical applications. The electrochemical behavior of MTZ at the 3D GNT-modified electrode was discussed in detail through cyclic voltammetry (CV) which suggested an irreversible reduction of nitro group to the corresponding hydroxylamine and a subsequently reversible redox peak for the corresponding...
Gold electrode modified with self-assembled monolayer of cysteamine-functionalized mwcnt and its application in simultaneous determination of dopamine and uric acid, Article Electroanalysis ; Volume 24, Issue 2 , February , 2012 , Pages 425-432 ; 10400397 (ISSN) ; Mahdavi Shakib, A ; Ghalkhani, M ; Saberi, R. S ; Sharif University of Technology
The voltammetric behavior of dopamine (DA) and uric acid (UA) on a gold electrode modified with self-assembled monolayer (SAM) of cysteamine (CA) conjugated with functionalized multiwalled carbon nanotubes (MWCNTs) was investigated. The film modifier of functionalized SAM was characterized by means of scanning electron microscopy (SEM) and also, electrochemical impedance spectroscopy (EIS) using para-hydroquinone (PHQ) as a redox probe. For the binary mixture of DA and UA, the voltammetric signals of these two compounds can be well separated from each other, allowing simultaneous determination of DA and UA. The effect of various experimental parameters on the voltammetric responses of DA and...
Electrodeposition of Copper Oxide Nanoparticles on Precasted Carbon Nanoparticles Film for Electrochemical Investigation of anti-HIV Drug Nevirapine, Article Electroanalysis ; Volume 27, Issue 8 , June , 2015 , Pages 1989-1997 ; 10400397 (ISSN) ; Kohansal, R ; Ghalkhani, M ; Amini, M. K ; Sharif University of Technology
Wiley-VCH Verlag 2015
This work describes the development of a novel electrochemical sensor based on electrodeposition of copper oxide nanoparticles onto carbon nanoparticle (CNP) film modified electrode for the analysis of the anti-HIV drug, nevirapine (NEV). The electrochemical experiments were performed using linear sweep and cyclic voltammetry. Atomic force microscopy was applied for surface characterization of the deposited modifier film (CuO-CNP) on glassy carbon electrode (GCE). No oxidation peak was observed for NEV on the bare GCE, but both CNP-GCE and CuO-CNP-GCE showed a distinctive anodic response towards NEV with considerable enhancement (276-fold and 350-fold, respectively) compared to CuO-GCE. The...
Voltammetric behavior and determination of trace amounts of omeprazole using an edge-plane pyrolytic graphite electrode, Article Iranian Journal of Pharmaceutical Research ; Volume 14, Issue 2 , Spring , 2015 , Pages 465-471 ; 17350328 (ISSN) ; Ghalkhani, M ; Bayat, M ; Ghorbani Bidkorbeh, F ; Sharif University of Technology
Iranian Journal of Pharmaceutical Research 2015
The voltammetric performance of edge-plane pyrolytic graphite (EPG) electrode via adsorptive stripping voltammetry was investigated for study of the electrochemical behavior of omeprazole (OMZ) in aqueous solution. The results revealed that the oxidation of OMZ is an irreversible pH-dependent process that proceeds with the transfer of one electron and one proton in an adsorption-controlled mechanism. The determination conditions, such as the pH values of the supporting electrolyte, accumulation time and scan rate were optimized. Simplicity, high reproducibility and low detection limit (3 nM) of the electrode response as well as wide linear range (0.01 to 4.0 µM) can be stated as significant...