Sharif Digital Repository

Knowledge is an organization asset that if used in the direction of organization’s strategic mission, can provide values for the organization. Therefore, many organizations such as NASA, Siemens; and Microsoft have invested in order to improve their knowledge management practices. Many organizations have not been successful in implementing appropriate knowledge management and incurred by huge expenses, while others can use and improve their locations among their competitors in the business. The reason behind many of these organizations were ignoring factor(s) that have direct undeniable effect on result from organization’s knowledge management.
The framework of knowledge management is a... 

The occurrence of the COVID-19 pandemic and the subsequent rising demand for purchasing alcohol-based sanitizers led to a remarkable prosperity in supplying these hygiene products. Hence, the development of a straightforward and efficient analytical strategy for discrimination of antiseptic alcohols including methanol, ethanol and isopropanol is of great importance. By exploiting the alcohol-sensitive membranes of probiotic bacteria, this research aims to develop a colorimetric sensor array for discriminating methanol, ethanol and isopropanol. In this design, the aggregation of citrate-capped gold nanoparticles (Au NPs) on the thiol-modified surface of two probiotic bacteria, including... 

DNA methylation in one of the most important epigenetic variations, which causes significant variations in gene expressions of mammalians. Our current knowledge about DNA methylation is based on measurments from samples of bulk data which cause ambiguity in intracellular differences and analysis of rare cell samples. For this reason, the ability to measure DNA methylation in single-cells has the potential to play an important role in understanding many biological processes including embryonic developement, disease progression including cancer, aging, chromosome instability, X chromosome inactivation, cell differentiation and genes regulation. Recent technological advances have enabled... 

Acceptance of new technologies in an industrial field generally takes a long time, and needs accelerators and facilitators to be thoroughly and truly understood, accepted, and then implemented. One of the most useful accelerators is Feasibility Study, which help the specialists to be confident that the whole technical and economic aspects of the issue are considered in an overall view and the technology is totally feasible and beneficial.Managed Pressure Drilling which was introduced as a new technology to drilling industry internationally in 2003 and developed rapidly till now, is one of the most useful technologies in the oil and gas wells drilling industry, and helps the Operator... 

In this dissertation, the value of distribution network reconfiguration in presence of distributed generation is investigated. In the first step, a mathematical optimization model is devised to minimize daily network losses via applying hourly reconfigurations. The results show that the hourly reconfiguration reduces the losses. Then, sensitivity analyses on the renewable penetration, wind and load correlation, switching cost and wind power prediction are conducted and discussed. The switching cost analysis revealed that a great amount of loss reduction could be attained with a small number of switching operations. The worthiness of reconfiguration becomes more in systems with high... 

In this dissertation, to improve the specifications of the available standoff imaging system in the THz and far-infrared Lab. of the electrical engineering department, we designed and analyzed some examples of reflective optical configurations as an optics of active millimeter-wave imaging systems. The superiority of reflective optics versus refractive optics due to the specifications such as loss reduction, broadband frequency response, proper aberration control, beam scanning capability, and easier transmitter and receiver positioning justifies the utilization of reflective configurations for designing millimeter-wave imaging optics. The defined design goals of this dissertation are as... 

Membrane bioreactors (MBRs) which are commonly understood as the combination of membrane filtration and biological treatment using activated sludge have several advantages, but membrane fouling reduces the membrane efficiency, permeability and lifetime. An alternative is replacing a moving bed biofilm reactor (MBBR) with the activated sludge system which may reduce the effect of membrane fouling. The sludge produced in MBBRs has poor settling characteristics, therefore, their efficiency is limited by the sedimentation tank performance and they require a larger settling surface. The combination of moving bed biofilm reactors and membrane bioreactors can compensate for the drawbacks of both of...