Sharif Digital Repository

Nowadays, due to the growing need of the human to further improve the health of the community, research in the field of pharmacology as well as simulation of the cell culture environment is increasing. One of the most important requirements for simulating cell culture is the use of concentration gradient in culture media. The reason for this is the dependence of cellular activity on the presence of a gradient of concentration in the environment. Also, in drug investigations, in order to speed up the examination of different drugs and reduce the amount of drug that will used, different concentrations of the drug should be considered simultaneously in the microchips. Therefore, to make the...