Sharif Digital Repository

The in vitro endothelial response of human umbilical vein endothelial cells was investigated on a poly (caprolactone)-based polyurethane surface vs an in situ TiO2-polyurethane nanocomposite surface, which has been produced as scaffolds for artificial vascular graft. The in situ synthesis of TiO2 nanoparticles in polyurethane provided surface properties that facilitated cellular adhesion, cell sensing, cell probing and especially cell migration. Cells on the nanocomposite surface have elongated morphology and were able to produce more extracellular matrix. All of these advantages led to an increase in the rate of endothelialization of the nanocomposite scaffold surface vs pure polyurethane.... 

A flexible, porous and biocompatible titanium dioxide nanotubes (TNT) - polyurethane (PU) film has been produced as a new scaffold for artificial vascular grafts. Synergistic improvements in the properties of vertical TNT and PU was reached, including enhancements in their biocompatibility, mechanical strength, flexibility and porosity. Open-ended (OE) TNT-PU and close-ended (CE) TNT-PU films were synthesized and their mechanical and biological properties were compared with their pure PU counterparts. TNT were attached to PU with a new strategy. The resulting flexible structure was hydrophilic and super hydrophilic in OE-TNT-PU and CE-TNT-PU scaffolds, respectively. The gas leakage during... 

A special type of shell structure - a concrete shallow funicular shell of circular plan - is considered in this paper. Funicular shells carry their dead weight only by in-plane compression forces. Numerical analysis of funicular shells was performed using the non-linear finite-element method, considering both geometric and material non-linearities. A circular-plan concrete funicular shell unit was also constructed and its ultimate central concentrated load is determined. The ultimate load of the shell unit predicted by the numerical model was very close to the experimentally determined ultimate load, thus confirming the validity of the numerical model. The numerical results revealed the... 

This paper considers a realistic multi-service system design problem in which each service type is a stochastic sequence of services provided by different units of facilities where each facility is modeled as a set of open Jackson queueing networks. The problem is first formulated as a mixed-integer nonlinear programming model, which is further simplified to a model with a smaller number of constraints. Three exact solution methods are applied to solve the amended model. The first one is a cutting-plane method, which is based on a piecewise-linear approximation. The second is based on a mixed-integer linear programming formulation, which is enhanced by valid inequalities. The third is to use... 

One of the underlying factors in the conservation and development of urban green spaces is the available water resources use for green areas in each region. The primary purpose of this study is to introduce the integration of a proper simulation method for runoff along with AHP-PROMETHEE decision-making method for water resources management in urban basins. The application of this approach was investigated in the city Buin Zahra of Qazvin Province of Iran. In the first step by using the analytic hierarchy process (AHP), the available water resources in the case study were weighted. In the second step, the water resources of the municipal and residential wells and water collected by... 

One of the underlying factors in the conservation and development of urban green spaces is the available water resources use for green areas in each region. The primary purpose of this study is to introduce the integration of a proper simulation method for runoff along with AHP-PROMETHEE decision-making method for water resources management in urban basins. The application of this approach was investigated in the city Buin Zahra of Qazvin Province of Iran. In the first step by using the analytic hierarchy process (AHP), the available water resources in the case study were weighted. In the second step, the water resources of the municipal and residential wells and water collected by... 

One of the most important capabilities expected from an autonomous vehicle is avoiding collision with obstacles in its path. For this purpose, autonomous vehicle must be able to perform an emergency maneuver as soon as the obstacle is detected. This paper presents a method for designing and performing an emergency maneuver in order to avoid collision with a fixed or moving obstacle in the path. A sinusoidal or exponential trajectory, which is a function of the relative distance between vehicle and obstacle, is designed as the desired trajectory for lateral motion of the vehicle. A sliding mode controller is designed in order to guarantee that the vehicle tracks that desired trajectory. The... 

In this paper, a method for overtaking stationary and moving obstacles will be introduced. The method consists of designing a desired trajectory for lateral motion of the vehicle and then using a lateral motion controller for tracking this desired trajectory. The desired trajectory is a sigmoid exponential function of relative distance between the vehicle and the obstacle and guarantees overtaking the obstacle, if tracked exactly, despite of lateral and longitudinal motions of the obstacle. Lateral acceleration of the vehicle should not exceed safety limits during tracking desired trajectory. This matter has been used as a decision criterion for determining feasible and unfeasible desired... 

Outpatient appointment scheduling problems have recently gained increasing attention. This paper provides a comprehensive review of recent analytical and numerical optimization studies that present decision-support tools for designing and planning outpatient appointment systems (OASs). A structure for organizing the recent literature according to various criteria is provided, including a framework that classifies decisions at the strategic, tactical, and operational levels. The OAS literature is evaluated from four perspectives: problem settings, environmental factors, modeling approaches, and solution methods. In addition, research gaps and areas of opportunity for future research are... 

The sustainable retrofit options may significantly improve the energy consumption and the environmental impacts of the existing buildings. This paper presents a multi objective optimization framework to reach the minimum economic costs and Global Warming Potential (GWP) impact of existing buildings. New energy-efficient technologies for the supply side of the energy system are considered which may minimize life cycle environmental impacts of buildings. Two educational buildings in the campus of Sharif University of Technology are studied. The results show that utilizing reciprocating engine and exhaust-fired absorption chiller reduce the GWP to 133 tons (17.79% of reduction) and 190 tones... 

Microbial desalination cell (MDC) is a new bio-electrochemical technique which converts chemical energy into electrical energy, and at the same time desalinates water and treats wastewater. In this study, MDC performance and water biofouling conditions were tested as an efficient pretreatment desalination process of reverse osmosis (RO). The experiments were designed in a three-chamber reactor to compare the performance of batch and continuous fed modes, using bio-cathode and synthetic wastewater in four different hydraulic retention times and 17 and 35 g/L NaCl concentrations. According to the results, maximum salt removal of about 52.3% was obtained in the continuously fed MDC at 35 g/L... 

This study evaluates the effectiveness of adsorption process by Granular Activated Carbon (GAC) compared with a novel formulation of coagulation - flocculation process for dye removal from textile wastewater. In this regard, acidic, reactive, disperse and direct red dye are used to prepare the synthetic dye. Dominant wave length for each dye is determined by spectrophotometeric method. Using GAC as adsorbent, equilibrium time and adsorption isotherm of each dye are determined with aid of spectrophotometric method. The results show that GAC can not remove dispersed red dye. Acidic red, direct red and reactive red of 5 mg/L concentration are removed by GAC up to %90, %88 and %43 in 30, 60 and...