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    Development of sol-gel-derived multi-wall carbon nanotube/hydroxyapatite nanocomposite powders for bone substitution

    , Article Journal of Composite Materials ; Vol. 48, issue. 4 , February , 2014 , pp. 483-489 ; ISSN: 00219983 Hooshmand, T ; Abrishamchian, A ; Najafi, F ; Mohammadi, M ; Najafi, H ; Tahriri, M ; Sharif University of Technology
    Abstract
    Carbon nanotubes with unique physical and mechanical properties have shown great potential for biological applications, including tissue engineering and mimicking the structure and properties of human bones. In the present work, sol-gel synthesized nanocomposite powder of multi-wall carbon nanotube/hydroxyapatite characterized using field-emission scanning electron microscopy, transmission electron microscope, X-ray diffraction, Fourier transform infra-red spectroscopy and thermal analyses. The results show homogenous dispersion of nanotube in well-crystallized hydroxyapatite ceramic matrix. Scanning electron microscopy and transmission electron microscope observations show the sodium... 

    Effect of tool travel and rotation speeds on weld zone defects and joint strength of aluminium steel lap joints made by friction stir welding

    , Article Science and Technology of Welding and Joining ; Volume 17, Issue 2 , 2012 , Pages 162-167 ; 13621718 (ISSN) Movahedi, M ; Kokabi, A. H ; Seyed Reihani, S. M ; Najafi, H ; Sharif University of Technology
    2012
    Abstract
    In this study, Al-5083 and St-12 alloy sheets were friction stir lap welded at different travel (7- 23 cm min -1) and rotation (750-1125 rev min -1) speeds of the welding tool. The welded joints were characterised by various methods including shear tensile and Vickers microhardness tests, optical and scanning electron microscopies and X-ray diffraction analysis. The results showed that the weld zone defects decreased, and the joint strength also improved significantly with the reducing tool travel speed from 23 to 7 cm min -1. The travel speed of 11 cm min -1 was an optimum speed within the travel speeds investigated in this work. Additionally, raising the tool rotation speed enhanced the... 

    Mechanical and microstructural characterization of A1-5083/St-12 lap joints made by friction stir welding

    , Article Procedia Engineering, 5 June 2011 through 9 June 2011 ; Volume 10 , June , 2011 , Pages 3297-3303 ; 18777058 (ISSN) Movahedi, M ; Kokabi, A. H ; Seyed Reihani, S. M ; Najafi, H ; Sharif University of Technology
    2011
    Abstract
    Al-5083 and St-12 alloys sheets were friction stir lap welded at various travel and rotation speeds of the welding tool. Microscopic examinations indicate that the joint strength is due to the macroscopic and microscopic mechanical lockings and also atomic diffusion. The reaction zone of the welded joints consists of mixed layers of ultra-fine grains and the intermetallic compounds. The microhardness and nano indentation results prove that the intermetallic phase layer is more brittle in comparison to base metals and ultra-fine grain region. The fracture surfaces are a combination of brittle and ductile fractures. The fracture loads show that the joint strength improves significantly by... 

    Effect of dwell time on joint interface microstructure and strength of dissimilar friction stir spot-welded al-5083 and st-12 alloy sheets

    , Article Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science ; Volume 48, Issue 4 , 2017 , Pages 1744-1758 ; 10735623 (ISSN) Fereiduni, E ; Movahedi, M ; Kokabi, A. H ; Najafi, H ; Sharif University of Technology
    Springer Boston  2017
    Abstract
    Joining of Al-5083 alloy sheet to St-12 steel sheet was performed using a new friction stir spot welding (FSSW) technique in which the tool pin tip did not enter lower steel sheet. Effect of dwell time on the microstructure and mechanical properties of the joints was studied by various methods including microhardness measurements, shear test, stereo and light microscopy as well as scanning and transmission electron microscopy (SEM and TEM). Results indicated that compared to the conventional FSSW process, stronger joints can be achieved by this FSSW technique. Cross-sectional observation of the failed specimens indicated the occurrence of final fracture from the circumference of the tool pin... 

    Growth kinetics of Al-Fe intermetallic compounds during annealing treatment of friction stir lap welds

    , Article Materials Characterization ; Vol. 90 , April , 2014 , pp. 121-126 ; ISSN: 10445803 Movahedi, M ; Kokabi, A. H ; Seyed Reihani, S. M ; Najafi, H ; Farzadfar, S. A ; Cheng, W. J ; Wang, C. J ; Sharif University of Technology
    Abstract
    In this study, we explored the growth kinetics of the Al-Fe intermetallic (IM) layer at the joint interface of the St-12/Al-5083 friction stir lap welds during post-weld annealing treatment at 350, 400 and 450 C for 30 to 180 min. Optical microscope (OM), field emission gun scanning electron microscope (FEG-SEM) and transmission electron microscope (TEM) were employed to investigate the structure of the weld zone. The thickness and composition of the IM layers were evaluated using image analysis system and electron back-scatter diffraction (EBSD), respectively. Moreover, kernel average misorientation (KAM) analysis was performed to evaluate the level of stored energy in the as-welded state.... 

    A novel panel of blood-based microRNAs capable of discrimination between benign breast disease and breast cancer at early stages

    , Article RNA Biology ; 2021 ; 15476286 (ISSN) Sadeghi, H ; Kamal, A ; Ahmadi, M ; Najafi, H ; Sharifi Zarchi, A ; Haddad, P ; Shayestehpour, B ; Kamkar, L ; Salamati, M ; Geranpayeh, L ; Lashkari, M ; Totonchi, M ; Sharif University of Technology
    Taylor and Francis Ltd  2021
    Abstract
    Breast cancer (BC) as a leading cause of cancer death among women, exhibits a wide range of genetic heterogeneity in affected individuals. Satisfactory management of BC depends on early diagnosis and proper monitoring of patients’ response to therapy. In this study, we aimed to assess the relation between the expression patterns of blood-based microRNAs (miRNAs) with demographic characteristics of the patients with BC in an attempt to find novel diagnostic markers for BC with acceptable precision in clinical applications. To this end, we performed comprehensive statistical analysis of the data of the Cancer Genome Atlas (TCGA) database and the blood miRNome dataset (GSE31309). As a result,...