Sharif Digital Repository

In this article, the problem of mixed convection in vertical rectangular microchannels for both regular fluids and nanofluids have been solved, using the CFD technique in the entrance regions of momentum and heat transfer taking in account the influences of viscous heating, inertial force and sleep conditions. In case of nanofluid flow, both the Brownian and thermophoresis molecular transfer mechanisms were considered.The predicted results were validated using fully developed distributions of velocity and temperature. Furthermore, the influences of mixed convection parameter (Gr/Re) and Kn number values on distributions of velocity and temperature through the entrance and fully-developed... 

Nowadays, advanced and inexpensive pre-clinical methods for investigating the effects of anti-cancer drugs are expanding. One of the latest three-dimensional laboratory modeling for evaluating the effects of drugs is the use of tumor-on-chip technology, which actually models the physiological system of the body through three-dimensional scaffolds, multicellular cultures, and shaped vascular systems. In this study, three-dimensional culture of cancer cells was performed in the form of spheroids. A chip of U-shaped microstructures with and without gaps was used to trap cells and form cancer spheroids. We simulated the simultaneous effect of drug and oxygen concentration distribution inside the... 

Prediction of shear plane angle is a way for prediction of the mechanism of chip formation, machining forces and so on. In this study, Merchant, Corrected Merchant, Lee and Shaffer, Lee and Shaffer with Built up Edge, Corrected Lee and Shaffer and Slip line theories are used for prediction of shear plane angles and cutting forces in machining of Al/SiCp metal matrix composite. The experimental cutting forces are compared with the calculated cutting force based on shear plane angles extracted from Merchant, Corrected Merchant, Lee and Shaffer, Lee and Shaffer with Built up Edge, Corrected Lee and Shaffer and Slip line theories. The variation of these cutting forces with cutting speed, feed... 

Data collected from street networks show that travel time in urban street networks is a stochastic variable, whose range of variation increases with the congestion level. Work and school trips comprise the major part of morning peak volumes, whose common characteristic is that they need to be made on time. For this reason, these travelers are pessimistic in their route choice, and try to choose routes which are more reliable. Travel time standard deviation is one of the common measures for estimating travel time reliability that is related to properties of day-to-day travel time distribution on a particular route. Based on the empirical data collected from Tehran street network, this paper... 

Noise or noise pollution, is defined as an unwanted sound, produced mostly by motor vehicles in urban areas. If the noise exceeds its limit, adverse effects on users and citizens are expected. Thus the assessment of the noise level and its comparison with allowable values is mandatory. Traffic induced noise depends upon different factors such as traffic, weather, and, sound barriers. Noise pollution study has a long history all over the world. Many studies, mostly representing the outdoor noise pollution models, have been done in recent years. This paper presents an assessment of traffic-induced noise in a heavily traveled tunnel, locally referred to as Resalat tunnel, which is located in... 

In this thesis, we introduce a novel Artificial Intelligence (AI) system inspired by the philosophical and psychoanalytical concept of imagination as a ``Re-construction of Experiences". Our AI system is equipped with an imagination-inspired module that bridges the gap between textual inputs and other modalities, enriching the derived information based on previously learned experiences. A unique feature of our system is its ability to formulate independent perceptions of inputs. This leads to unique interpretations of a concept that may differ from human interpretations but are equally valid, a phenomenon we term as ``Interpretable Misunderstanding". We employ large-scale models,... 

With the advancement of automotive industry, the number of electronic systems that need to communicate with each other has increased. An effective strategy to meet these growing demands is using bus-based protocols, which can establish safe communication among numerous nodes with reasonable cost, weight, and space requirements. The objective of this thesis is the design and implementation of a transceiver based on the FlexRay protocol. The significance of this protocol lies in its ability to provide higher data transmission rates compared to other protocols like CAN and LIN, and its role as the foundational communication medium among various domains in modern vehicle architectures. In this... 

Modeling and performance evaluation of the real time distributed systems is a significant problem. Stochastic activity network is one of the high level models used for this purpose. This network is an extension of generalized stochastic Petri net which is more powerful and flexible than other Petri net extensions. Checking the satisfiability of properties such as performance, dependability and user's expected properties is considerable in these models. Thus, using the approaches and generating modeling and model checking tools with the mentioned purpose is attractive. A model checker automatically checks the correctness of the system behaviors as properties against the model by getting the... 

Cardiovascular diseases are among the leading causes of death worldwide. For instance, in 2015, almost 31% of the world’s mortality rate was due to these causes. One of these diseases is cardiac coronary vessels’ occlusion which leads to the insufficient blood supply to the heart tissue and cardiomyocytes death after Myocardial Infarction (MI). After MI, a hierarchy of events in the heart tissue changes heart muscle and forms cardiac fibrosis. This fibrotic tissue does not have the native one’s properties and function, so it will cause cardiac arrest and patient death. Therefore, it is obvious that vascular network plays a crucial role in the heart function. The importance of cardiac... 

This study has focused on the important problem of landing on a planet as an important current and future space mission. In this regard, dynamics modeling and integrated state estimation and control problems have been investigated in different views. To this aim, first a novel concurrent representation for translational and rotational kinematics has been developed based on the extension of modified Rodrigues parameters to dual space. This parameter set, called dual modified Rodrigues parameters (DMRP), is then utilized to establish an integrated roto-translational dynamic. The proposed DMRP-based kinematics and dynamics have been verified via comparison to traditional methods of... 

This thesis addresses the problem of optimal distributed control of unknown interconnected systems. In order to deal with this problem, a data-driven learning framework for finding the optimal centralized and the suboptimal distributed controllers has been developed via convex optimization.First of all, the linear quadratic regulation (LQR) problem is formulated into a nonconvex optimization problem. Using Lagrangian duality theories, a semidefinite program is then developed that requires information about the system dynamics. It is shown that the optimal solution to this problem is independent of the initial conditions and represents the Q-function, an important concept in reinforcement... 

Accurate and fast attitude estimation of a rigid body plays an essential role in the performance of a vehicle’s control system, especially aerospace vehicles. Ample works have been done to increase the accuracy and speed of the attitude estimation process, but all have been developed according to a model-based approach. This approach assumes that the torques acting on the body have a known dynamical model that is used for the attitude estimation. The purpose of the present research is to estimate the attitude via a model-free approach, i. e. dynamics of the torques acting on the body are no longer assumed to be known, and its learning is the next step. Thus, the problem formulation of this... 

This thesis presents a new approach to design structural output feedback controllers with stabilization and pole-placement at desired points on the S plane. It is assumed that the linear time-invariant system has no fixed mode corresponding to the specified control structure, outside the desired region of the closed-loop poles, such that the structural controller design problem is theoretically feasible. To this end, the structural output controller design problem is first transformed into a structurally equivalent problem based on the solution of a set of discrete linear programs. Then, by using the resultant structure, a new method is proposed for designing static and dynamic control loops... 

Cardiovascular disease (CVD) currently remains a considerable challenge for clinical treatments. CVDs account for N17.5 million deaths per year and will predictably increase to 23.6 million by 2030. The main purpose is to create human model systems to study the effect of disease mutations or drug treatment on the heart. In addition, engineered cardiac tissues are considered promising candidates to be transplanted to improve the function of diseased hearts. For engineered active tissues/organs, 3D bioprinting can fabricate complex tissue architecture with a spatiotemporal distribution of bioactive substances (cells, growth factors, and others) to better guide tissue regeneration. However,... 

Understanding biological systems requires extensive knowledge of individual parameters, and to study the processes of cell differentiation and cell behavior, a suitable environment must be created with the physiological conditions of the human body. For this purpose, with the knowledge of microfluidics, a microenvironment can be provided to study the behavior of cells on a small scale. The use of bone tissue model microfluidic chips is an alternative and new method in which it is possible to study the behavior of cells to differentiate into bone and to examine the toxicity of drugs, which in itself can help in the effective and successful treatment of these cases show. Therefore, in this...