Sharif Digital Repository

In this dissertation, a vast number of 2D steel IMFs (Intermediate Moment Frames) with various number of stories and bays, each having one soft storey, of various intensities (ordinary soft storey & extreme soft storey), were studied. The frames were loaded according to ASCE SEI-7-16 and were designed based on AISC-360-10. In order to make a storey softer than others, its height was increased with respect to those of other ones. The dynamic ‘nonlinear spectral analysis,’ and two different static approaches, namely those of ‘ASCE/SEI-7-90’ and ‘ASCE/SEI-7-16,’ were used to study the frames. Comparison of the results obtained from the three aforementioned methods, one dynamic and two static... 

Nowadays environmental issues are of great importance and one of the most paramount issues is the quality of water, because clean water is vital to our existence. Besides different methods for water purification, water quality testing is a useful and needful tool. Traditional methods for determination of water quality parameters are mainly expensive, time consuming and require highly trained staff. In this study, we have described a centrifugal microfluidic platform (Lab- on – a- CD) for simultaneous determination of different physical and chemical parameters including Nitrite, Free Chlorine and pH. All of the processes from sample injection to detection are integrated on this low-cost and... 

Nowadays, cancer, which has been mentioned as the disease of the century, is the second leading cause of death throughout the world, and its incidence is constantly increasing. Isolation of circulating tumor cells is one of the most critical steps in diagnosing and controlling cancer progression. Due to the rarity of cancer cells compared to other cells in the blood sample, the isolation process requires optimal and high-precision devices. With the advent of inertial microfluidics, the ability to control the particles movement, the processing of blood samples as quickly and accurately as possible, and the viability of cells with a high percentage, introduced microfluidic systems as a... 

The prediction of deposition efficiency of submicron particles in the pulmonary alveoli has received special attention due to its importance for drug delivery systems, and for assessing air pollutants health risks. In this work, the pulmonary alveoli of a healthy human are idealized by a three dimensional honeycomb like configuration and a fluid-structure interaction analysis is performed to study the normal cyclic breathing hydrodynamics. A viscoelastic model is used for the mechanical behavior of alveolar wall tissue. In contrast to previous works in which the inlet flow rate is predefined, in this model a negative pressure is imposed on the outside surface of the alveolus which causes air... 

An acinus is defined as the complex of airways supplied by one first order respiratory or transitional bronchiole. In this part, the replenishment of oxygen at the alveolar surface occurs by a combination of convective air flow with diffusion of oxygen in the air. So for studying gas exchange in the lung, modeling gas species transport and exchange in an acinus is important. Due to lacking direct measurements of the distribution of oxygen (or carbon dioxide) concentration in the acinus, several mathematical models have been developed and studied by numerical simulations. But in none of them the influence of breathing pattern and the role of blood flow in restricting the gas exchange rate have... 

Planing crafts in waves are characterized by large and violent vertical motion and acceleration. The hull structure is subjected to high impact loads and the crew experiences high transient vertical acceleration and in most cases the crew needs to lower speed in order to avoid damage to the hull.In recent years, interest on increasingly faster marine vehicles has remarkably grown. Typical planing monohulls are: patrol vessels, pilot boats, rescue vessels, coast guard vessels and small navy vessels. So the behavior of planing monohulls in waves has been a widely researched topic since more and more planing monohulls appeared.The accurate prediction of large amplitude ship motions in severe... 

In this thesis, cavitating flow over 2D/3D geometries of cavitators and projectile bodies in stationary and moving conditions are simulated using the "Volume of Fluid" (VOF) technique. The main application of VOF model is for simulating free surface flows. In this work, another capability is added to the VOF algorithm to solve for gas phase and by applying analytical-numerical mass transfer models, cavitation phenomenon is simulated. The developed algorithm precisely simulates the geometrical parameters of supercavities such as dimension and shape in a wide range of cavitation numbers. In addition, the flow parameters of supercavity such as drag coefficient, pressure coefficient inside the... 

The present study examines both Direct Current (DC) and Alternating Current (AC) electroosmotic flows in a parallel plate microchannel. The method consists of a central finite difference scheme for spatial terms and a forward difference scheme for the temporal term. Asymmetric boundary conditions are assumed for Poison-Boltzmann equation used to determine the electric double layer (EDL) potential distribution. The potential distribution is then used to evaluate the velocity distribution for both DC and AC electroosmotic flows. The velocity distributions are obtained by applying slip boundary conditions on the walls to account for probable hydrophobicity of the surfaces. After determining the... 

In this thesis, the potential flow including unsteady partial cavitation around axisymmetric bodies are studied using a boundary element method (BEM) based on potential theory. For this purpose the wetted surface of the body and cavity surface are divided (approximated) to panels. Then, by applying the Green’s third identity and expressing this theory in potential flow around every surface, cavitation can be modeled by distributing the source and the dipole rings on cavity/body surface. In order to approaching this goal we introduced dipole rings distribution on the cavity and body surfaces and source rings distribution on the cavity surface. In this work the cavitation number is assumed to... 

Morphology and alignment of endothelial cells (ECs) have great influence on plaque formation. These alignments are based on the cyclic strains and wall shear stress (WSS) on the arterial wall. In the present study, cyclic strains and WSS are investigated to predict the secondary plaque locations downstream of the primary stenosis. Therefore, left coronary artery (LCA) with its branches to left anterior descending (LAD) and left circumflex (LCX) are 3D located on a virtual sphere to consider the cardiac motion. Stenoses are placed at the beginning of the bifurcation with varying degrees from 40% to 70% based on diameter reduction. Healthy coronary is also constructed to compare with those of... 

Aphron drilling fluids or CGA fluids are the wellknown updated drilling fluids in recent years.this kind of drilling fluids can control the mud loss into the formation and thus reduce formation damage and drilling costs. its structure consists of two phase fluid (gas and liquid) that the aphrons are the micro bubbles with 10 to 100 micrometer diameter that have strong stability in liquid phase compared to foamy drilling fluids. Generally aphron drilling fluids are made of base drilling fluid and surfactants, for more stability, mixed surfactant-polymer additive is so beneficial. in the last two decades, the Lattice-Boltazmann method is introduced for computational fluid dynamic area and... 

Performing research and development in the field of modern vessel types which serve several functions is considerably necessary because of their importance and rapid development. HARTH vessel is considered one of the important ships which has been recently attracted much attention from the world. In this respect, a full investigation of its performance could make a big contribution to its optimum design and appropriate exploitation.“HARTH” ship is the abbreviation for “High Aspect Ratio Twin Hull” is included in the catamaran vessel category with a high aspect ratio with respect to their underwater cross-section’s ratio of length to width.A host of crucial issues should be considered for... 

Microfluidic systems create great development in diseases and drug delivery in various organs of the body. In this study, human pulmonary alveolar cell performance was evaluated from the perspective of the cell culture using a microfluidic system. For this purpose, numerical simulations of the microchip channels flow field are very important to select appropriate models. So in the first step, the flow field and particle deposition were simulated. Then an optimal model was selected based on key parameters such as cell feeding, shear stress exerted on the cell, particles distribution and also the limitations and possibilities for constructing. The numerical results show that the shear stress,... 

Gas embolotherapy is a therapeutic method which is a suitable replacement for traditional embolotherapy techniques. This method is especially applicable for vascularized tumors which cannot be treated using other tumor treatments. In Gas embolotherapy technique, droplets made of Perfluorocarbon, whose evaporation temperature is below body temperature are injected into blood stream. The size of this droplets is chosen so that they can freely circulate in human vasculature and finally reach the specified target. At the target point, an ultrasound transducer is focused which causes the droplets to evaporate and turn into bubbles. During the evaporation process, bubbles expand volumetrically to... 

Improving the performance of modular, low-cost autonomous underwater vehicles (AUVs) in such applications as long-range oceanographic survey, autonomous docking, and shallow-water mine countermeasures requires improving the vehicles’ maneuvering precision and battery life. These goals can be achieved through the improvement of the vehicle control system. A vehicle dynamics model based on a combination of theory and empirical data would provide an efficient platform for vehicle control system development, and an alternative to the typical trial-and-error method of vehicle control system field tuning. As there exists no standard procedure for vehicle modeling in industry, the simulation of... 

The purpose of this study is extracting a dynamic model of longitudinal motions of high speed catamaran in regular and irregular waves, and then motion control of vessels by using of foil control elements and interceptor. For simulating longitudinal motions in regular waves, at first the longitudinal hydrodynamic coefficients of vessels should be extracted, then by substituting extracted coefficients in cumminz equation and using system identification methods, some equations are presented to estimate longitudinal two degree of freedom motions of high speed catamaran in waves. In this thesis the extraction of hydrodynamic coefficients is based on both numerical and experimental methods. ANSYS... 

A mechanical system inherently affected by the conditions, factors and parameters of uncertainty. Without including the uncertainty effects in the optimal design procedure, the mechanical system will not be reliable. To include uncertainty effects in an optimum design, there are two different approaches; the robust design optimization and the reliability based design optimization. In robust design optimization process, the main aim is to enhance the system performance by minimizing the variations. In reliability based design optimization process, the target is that the optimal design variables to be in appropriate reliably levels. In this paper, a new model for the reliability based robust... 

In this thesis ship propeller performance in maneuvering conditions have been investigated which means an oblique flow condition for working propeller. Then results of these investigations have been put to use to simulate maneuvering using MMG equations. These calculations have been done to investigate nominal wake variations in different drift angles and depth conditions. In this project displacement vessel KVLCC2 and propeller POTSDAM VP1304 have been studied due to the abundance of experimental data. Calculations in this study have been carried in three steps: 1, calculation of nominal wake of the vessel in different drift angles and depths via CFD. 2, Using the results of previous... 

Partially submerged propellers are new type of propellers which knowledges ragard them is limited. These propellers found a growing market ahead of them and expertsexpect to use these propellers for big vessels at high speeds. This type of propulsors do not lose their efficiences at high speeds and are assumped to be economical. Meanwhile due to continuosus hit to water surface, huge stresses are extered on tha blade witch needs to be fundamentally studied. Several researchers have studied the partially submerged propellers which unfortunately did not publish their results. Undergo less or more thrust and torques which in both cases the efficiency also increases. The use of numerical methods...