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yaghmaei--sohila
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Design of Amniotic Membrane-based Hydrogel for Cardiac Tissue Engineering Application
, M.Sc. Thesis Sharif University of Technology ; Yaghmaei, Sohila (Supervisor) ; Saadatmand, Maryam (Supervisor)
Abstract
Mammalian cardiac tissue lacks the ability to effectively self-regenerate following severe damage. The application of external therapeutic agents with strong mechanical properties is needed to restore its function. Even though conventional therapies have several challenges and limitations, injectable hydrogels, with minimally invasive, can significantly improve cardiac tissue regeneration. Extracellular matrices are the most appropriate biomaterials for synthesizing cardiac scaffolds. The human amniotic membrane obtained from the amniotic sac is a readily available, abundant, and inexpensive candidate that has been successfully utilized for the clinical treatment of cardiac diseases....