Sharif Digital Repository

Gold nanoparticles are potentially very attractive components for therapeutic delivery since they can be synthesized with any diameter from 1 to 200 nm to carry a payload of therapeutic molecules into a cell without triggering an immune response. Gold nanoparticles must undergo surface transformations before coupling to therapeutic molecules to become eligible for this purpose. It is now more understood that amine groups can bind to gold nanoparticles strongly, which has enabled surface modification of gold nanoparticles with amino acid lysine through its amine group. These lysine capped gold nanoparticles can further be coupled to therapeutic molecules for delivery purposes. In this study... 

In this paper, we investigate the CO emission from an oil refinery gas incinerator both theoretically and experimentally. At the beginning of this research, our collected data from this incinerator showed that the CO contamination would be far exceeding the permissible environmental standards at the stack exhaust. Therefore, we decided to perform a combined theoretical-experimental study to find a reasonable solution to reduce the CO pollution suitably. Our theoretical study showed that a reliable solution would be to increase the incinerator operating temperature. However, we needed to collect some data from this incinerator to examine if our achieved analytical solution would work... 

Carbon nanotubes are among promising components for a wide range of applications, due to their unique properties; Specifically, They are a new alternative and efficient tool for transporting and translocating therapeutic molecules since they can translocate easily into the cytoplasm or nucleus of a cell through its membrane without generating an immunogenic response and toxic effects. While pristine carbon nanotubes are insoluble in all solvents, the organic functionalisation of carbon nanotubes is the prerequisite for their solubility profiles and their manipulation into biological systems. For this purpose, in this study, we first report the Amide-functionalization of CNTs which a direct... 

The final goal in a perforation operation is achieving the maximum production and reducing perforation damage, using optimal completion process. The Dynamic Underbalanced Perforation (DUP) as one of the more recent completion technologies minimizes or even eliminates the perforation crushed zone by optimizing the well's dynamic underbalance. Dynamic underbalance is a transient underbalance process that occurs immediately after creation of the perforation tunnels. The modeling of this process is essential in designing the optimal configuration of the perforation charges to evaluate the perforation efficiency. In this study we propose a novel and efficient numerical method, to optimize the... 

A bacterial strain, FBHYA2, capable of degrading naphthalene, was isolated from the American Petroleum Institute (API) separator of the Tehran Oil Refinery Complex (TORC). Strain FBHYA2 was identified as Achromobacter sp. based on physiological and biochemical characteristics and also phylogenetic similarity of 16S rRNA gene sequence. The optimal growth conditions for strain FBHYA2 were pH 6.0, 30°C and 1.0% NaCl. Strain FBHYA2 can utilize naphthalene as the sole source of carbon and energy and was able to degrade naphthalene aerobically very fast, 48 h for 96% removal at 500 mg/L concentration. The physiological response of Achromobacter sp., FBHYA2 to several hydrophobic chemicals... 

A great deal of computational power and time is necessary for the simulation of highly heterogeneous fractured reservoirs with complicated geometry. Simulating such largescale complex reservoirs with both minimum time and maximum accuracy has consistently remained a topic of concern to reservoir simulation engineers worldwide. The currently used linear solvers in well-known commercial simulators that utilize classical methods such as Nested Factorization (NF) and Incomplete LU Factorization (ILU) as their preconditioners, all suffer from severe convergence problems in models with high heterogeneity and/or large number of non-neighbor connections. To overcome such problems, a novel Adaptive... 

For speeding up the complex fractured reservoir simulating, we have given more attention to reducing runtime and improving efficiency of the solver. In this work, we describe an improved and computationally efficient version of Newton's method, which reduces the non-linear iteration count, increases time steps, and furthermore reduces time spent in nonlinear loops of reservoir simulating. Safeguarded variants of Newton's method which have used in current reservoir simulators cannot guarantee convergence of the solution, especially in highly heterogeneous, detailed and fractured reservoirs. In such simulators time step chopping is often observed. From other hand, with growing complexity,... 

A great deal of computational power and time is necessary for simulating highly heterogeneous fractured reservoirs with complex geometry; the efficiency of these computations is a major subject especially in large-scale heterogeneous and fractured reservoirs. So, simulating large scale, complex and fractured reservoirs with both minimum time and maximum accuracy is the scope of current work. The BiCG-Stabilized solver preconditioned by CPR-AAMG has been developed to achieve acceptable results of high efficiency and robustness for large heterogeneous fractured Black-Oil models. The solver's efficiency is demonstrated in an Iranian fractured field model with heterogeneity. As an observation,... 

A readout box prototype for the CMS Hadron Forward calorimeter upgrade was built and tested in the CERN H2 beamline. The prototype was designed to enable simultaneous tests of different readout options for the four anode upgrade PMTs, new front-end electronics design and new cabling. The response of the PMTs with different readout options was uniform and the background response was minimal. Multi-channel readout options further enhanced the background elimination. Passing all the electronic, mechanical and physics tests, the readout box proved to be capable of providing the forward hadron calorimeter operational requirements in the upgrade era