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    A facile and convenient synthesis of 3-alkylidene-oxindoles bearing tetrahydropyrazine scaffold under catalyst-free conditions

    , Article Heteroatom Chemistry ; Volume 29, Issue 2 , March , 2018 ; 10427163 (ISSN) Matloubi Moghaddam, F ; Moafi, A ; Sharif University of Technology
    Wiley-Blackwell  2018
    Abstract
    A facile and efficient synthesis of 2-oxindole derivatives bearing tetrahydropyrazine scaffold has been developed. Using water as solvent without any additional acid or metal catalyst, easy work up and high yield of products are the main advantages of this protocol. © 2018 Wiley Periodicals, Inc