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Search for: 7-methyl-2-nitro-6a-14b-dihydro-6h-7h-14h-thiochromeno-3--2--5-6-thiopyrano-3-4-c-chromene-6-14-dione
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      A new domino Knoevenagel-hetero-Diels-Alder reaction: An efficient catalyst-free synthesis of novel thiochromone-annulated thiopyranocoumarin derivatives in aqueous medium

      , Article Tetrahedron ; Volume 66, Issue 45 , November , 2010 , Pages 8615-8622 ; 00404020 (ISSN) Matloubi Moghaddam, F ; Kiamehr, M ; Khodabakhshi, M. R ; Mirjafary, Z ; Fathi, S ; Saeidian, H ; Sharif University of Technology
      2010
      Abstract
      An efficient catalyst-free synthesis of novel pentacyclic thiochromone-annulated thiopyranocoumarin derivatives is achieved via domino Knoevenagel-hetero-Diels-Alder reaction of 4-hydroxy dithiocoumarin and O-acrylated salicylaldehyde derivatives in H2O as solvent. The products are formed in good yields with high regio- and stereo-selectivity  
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