Loading...
Search for:
acute-kidney-failure
0.005 seconds
Urine and serum NMR-based metabolomics in pre-procedural prediction of contrast-induced nephropathy
, Article Internal and Emergency Medicine ; Volume 15, Issue 1 , 2020 , Pages 95-103 ; Chashmniam, S ; Khoormizi, S. M. H ; Salehi, L ; Jamalian, S. A ; Nafar, M ; Kalantari, S ; Sharif University of Technology
Springer
2020
Abstract
Contrast induced nephropathy (CIN) has been reported to be the third foremost cause of acute renal failure. Metabolomics is a robust technique that has been used to identify potential biomarkers for the prediction of renal damage. We aim to analyze the serum and urine metabolites changes, before and after using contrast for coronary angiography, to determine if metabolomics can predict early development of CIN. 66 patients undergoing elective coronary angiography were eligible for enrollment. Urine and serum samples were collected prior to administration of CM and 72 h post procedure and analyzed by nuclear magnetic resonance. The significant differential metabolites between patients who...