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      A simple approach to the synthesis of 3-substituted rhodanines and thiazolidine-2,4-diones

      , Article Scientia Iranica ; Volume 20, Issue 6 , 2013 , Pages 1833-1838 ; 10263098 (ISSN) Aryanasab, F ; Shokri, A ; Saidi, M. R ; Sharif University of Technology
      Sharif University of Technology  2013
      Abstract
      A novel synthesis of 3-substituted rhodanine and thiazolidine-2,4-dione derivatives, starting from aliphatic primary amines, carbon disulfide, and methyl 2-bromoacetate, is described. The reaction proceeds successfully both in water and under solvent-free conditions, but 2-thioxothiazolidin-4-one (rhodanine) derivatives were obtained under solvent free-conditions, and thiazolidine-2,4-dions were formed when water was used as the solvent  
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