Sharif Digital Repository

Nanofibrous structures mimicking the native extracellular matrix have attracted considerable attention for biomedical applications. The present study aims to design and produce drug-eluting core-shell fibrous scaffolds for wound healing and skin tissue engineering. Aloe vera extracts were encapsulated inside polymer fibers containing chitosan, polycaprolactone, and keratin using the co-axial electrospinning technique. Electron microscopic studies show that continuous and uniform fibers with an average diameter of 209 ± 47 nm were successfully fabricated. The fibers have a core-shell structure with a shell thickness of about 90 nm, as confirmed by transmission electron microscopy. By... 

This study evaluated the efficiency of different Digital Elevation Models (DEMs), including ALOS-12.5 m, SRTM-30 m, SRTM-90 m, and ASTER-30 m v3 when being applied for the hydraulic simulation of flood inundation areas. HEC-RAS-2D model was employed to simulate inundation extent of a 400-year flood (Mar 17, 2019, with peak discharge ~ 547.92 m3/s) along 70 km reach of low-gradient Gorganrood River, northeastern Iran. Fit percentage indicator (FI) and BIAS percentage indicator (BI) were used to evaluate the results in comparison with the remotely sensed inundated area data. The results revealed that the accuracy and capability of the ALOS and SRTM-30 m were higher in simulation of flood...