Loading...
Search for:
antigen-antibody-reactions
0.002 seconds
An artificial immune system with partially specified antibodies
, Article 9th Annual Genetic and Evolutionary Computation Conference, GECCO 2007, London, 7 July 2007 through 11 July 2007 ; Pages 57-62 , 2007 ; 9781595936974 (ISBN) ; Bagheri ShourakiS, S ; Jalali Heravi, M ; Jafari Jashmi, B ; Sharif University of Technology
2007
Abstract
Artificial Immune System algorithms use antibodies which fully specify the solution of an optimization, learning, or pattern recognition problem. By being restricted to fully specified antibodies, an AIS algorithm can not make use of schemata or classes of partial solutions. This paper presents a symbiotic artificial immune system (SymbAIS) algorithm which is an extension of CLONALG algorithm. It uses partially specified antibodies and gradually builds up building blocks of suitable sub-antibodies. The algorithm is compared with CLONALG on multimodal function optimization and combinatorial optimization problems and it is shown that it can solve problems that CLONALG is unable to solve....
Electrospray: novel fabrication method for biodegradable polymeric nanoparticles for further applications in drug delivery systems
, Article NANOCON 2009 - 1st International Conference, Conference Proceedings ; 2009 , Pages 324-331 ; 9788087294130 (ISBN) ; Vossoughi, M ; Sharif University of Technology
TANGER Ltd
2009
Abstract
Electrospray is an old processing technique that has recently been rediscovered. This technology is revolutionizing the biomaterials and nanotechnology fields by opening up new areas of research in fabricating drug delivery nano-devices. Due to their size, nanoparticles have the advantage of reaching less accessible sites in the body by escaping phagocytosis and entering tiny capillaries. Nanoparticles also have the unique property to accumulate at the site of inflammation and therefore, are very suitable for targeted drug delivery. The feasibility of fabricating relatively monodispersed polymeric nanoparticles by electrospray method in a modified electrospray setup is demonstrated in this...
Label-Free real-time detection of HBsAg using a QCM immunosensor
, Article Clinical Laboratory ; Volume 68, Issue 4 , 2022 , Pages 707-720 ; 14336510 (ISSN) ; Ghavidel, A ; Ahangari Cohan, R ; Hamidi Fard, M ; Khoobi, M ; Aghasadeghi, M ; Norouzian, D ; Sharif University of Technology
Verlag Klinisches Labor GmbH
2022
Abstract
Background: Hepatitis B virus surface antigen (HBsAg) is an important protein in both diagnosis and prevention of hepatitis B infection. In the current study, a piezoelectric immunosensor based on antibody-antigen interaction was designed to detect HBsAg. A quartz crystal microbalance system was employed to detect antibody-antigen interaction. Methods: At first, an oscillator was designed to measure the resonant frequency affected by the reactants using IC 74LVC1GX04. Antibody against HBsAg was immobilized on 10 MHz AT-cut quartz crystal. The surface modifications were monitored by atomic force microscopy (AFM) and contact angle measurements. Different concentrations of antibody were used...