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    A combined dynamical sequential network for generating coupled cardiovascular signals with different beat types

    , Article ; 2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies, ISABEL 2010, 7 November 2010 through 10 November 2010 , 2010 ; 9781424481323 (ISBN) Sayadi, O ; Shamsollahi, M. B ; Sharif University of Technology
    Abstract
    We present generalizations of the previously published artificial models for generating abnormal cardiac rhythms to provide simulations of coupled cardiovascular (CV) signals with different beat morphologies. Using a joint dynamical formulation, we generate the normal morphologies of the cardiac cycle using a sum of Gaussian kernels, fitted to real CV recordings. The joint inter-dependencies of CV signals are introduced by assuming the same angular frequency and a phase coupling. Abnormal beats are then specified as new dynamical trajectories. An ergadic first-order Markov chain is also used for switching between normal and abnormal beat types. Probability transitions can be learned from... 

    Development of an Integrated Hybrid Model of Human Cardiovascular and Respiratory System for Control Study purposes

    , M.Sc. Thesis Sharif University of Technology Kehtari, Payam (Author) ; Bozorgmehri, Ramin (Supervisor)
    Abstract
    Mathematical models are used for describing physical systems to make it possible to study and investigate the behavior of these systems and compare their performance and improve them. For this reason, a mathematical model for cardiovascular system and respiratory system is used to study how these two systems interact. The cardiovascular system model and the respiratory system model comprise four and two compartments, respectively. In fact, the combined model contains the left and right ventricles, body tissue, lung, systemic blood circulation, and pulmonary compartments. Heart rate and alveolar ventilation are assumed to be the quantities through them the central nervous system controls the... 

    Mathematical modeling of heart rate and blood pressure variations due to changes in breathing pattern

    , Article 2013 20th Iranian Conference on Biomedical Engineering, ICBME 2013, Tehran, 18 December 2013 through 20 December 2013 ; 2013 , Pages 54-58 Goldoozian, L. S ; Zahedi, E ; Sharif University of Technology
    IEEE Computer Society  2013
    Abstract
    Analysis of the heart rate (HR) variation due to respiration, known as respiratory sinus arrhythmia (RSA), is a method to assess the autonomic nervous system (ANS) function. In this paper a physiologically-based mathematical model consisting of the cardiorespiratory system and ANS control has been used in order to study the cardiovascular response (mean arterial blood pressure and HR) to breathing with different respiration rates and tidal volumes. Simulation results show that RSA has its maximal amplitude at the respiration frequency of 0.12 Hz and that RSA amplitude varies linearly by tidal volume. These results are in agreement with real data from the literature. In addition, the... 

    Utility of a nonlinear joint dynamical framework to model a pair of coupled cardiovascular signals

    , Article IEEE Journal of Biomedical and Health Informatics ; Volume 17, Issue 4 , 2013 , Pages 881-890 ; 21682194 (ISSN) Sayadi, O ; Shamsollahi, M. B ; Sharif University of Technology
    2013
    Abstract
    We have recently proposed a correlated model to provide a Gaussian mixture representation of the cardiovascular signals, with promising results in identifying rhythm disturbances. The approach provides a transformation of the data into a set of integrable Gaussians distributed over time. Looking into the model from a new joint modeling perspective, it is capable of assembling a filtered estimation, and can be used to derive temporal information of the waveforms. In this paper, we present a step-by-step derivation of the joint model putting correlation assumptions together to conclude a minimal joint description for a pair of ECG-ABP signals. We then probe novel applications of this model,... 

    Mathematical modeling of CSF pulsatile hydrodynamics based on fluid-solid interaction

    , Article IEEE Transactions on Biomedical Engineering ; Volume 57, Issue 6 , 2010 , Pages 1255-1263 ; 00189294 (ISSN) Masoumi, N ; Bastani, D ; Najarian, S ; Ganji, F ; Farmanzad, F ; Seddighi, A. S ; Sharif University of Technology
    2010
    Abstract
    Intracranial pressure (ICP) is derived from cerebral blood pressure and cerebrospinal fluid (CSF) circulatory dynamics and can be affected in the course of many diseases. Computer analysis of the ICP time pattern plays a crucial role in the diagnosis and treatment of those diseases. This study proposes the application of Linninger et al.s [IEEE Trans. Biomed. Eng. , vol. 52, no. 4, pp. 557565, Apr. 2005] fluidsolid interaction model of CSF hydrodynamic in ventricular system based on our clinical data from a group of patients with brain parenchyma tumor. The clinical experiments include the arterial blood pressure (ABP), venous blood pressure, and ICP in the subarachnoid space (SAS). These...