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asthma
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Classification of asthma based on nonlinear analysis of breathing pattern
, Article PLoS ONE ; Volume 11, Issue 1 , 2016 ; 19326203 (ISSN) ; Ghafari, T ; Darooei, R ; Nazari, M ; Mahdaviani, S. A ; Eslaminejad, A. R ; Almasnia, M ; Gharibzadeh, S ; Mani, A. R ; Hajizadeh, S ; Sharif University of Technology
Public Library of Science
2016
Abstract
Normal human breathing exhibits complex variability in both respiratory rhythm and volume. Analyzing such nonlinear fluctuations may provide clinically relevant information in patients with complex illnesses such as asthma. We compared the cycle-by-cycle fluctuations of inter-breath interval (IBI) and lung volume (LV) among healthy volunteers and patients with various types of asthma. Continuous respiratory datasets were collected from forty agematched men including 10 healthy volunteers, 10 patients with controlled atopic asthma, 10 patients with uncontrolled atopic asthma, and 10 patients with uncontrolled non-atopic asthma during 60 min spontaneous breathing. Complexity of breathing...
Asthma induces psychiatric impairments in association with default mode and salience networks alteration: A resting-state EEG study
, Article Respiratory Physiology and Neurobiology ; Volume 300 , 2022 ; 15699048 (ISSN) ; Salimi, M ; Nazari, M ; Tabasi, F ; Bamdad, S ; Dehdar, K ; Mikaili, M ; Mahdaviani, S. A ; Salari, F ; Lookzadeh, S ; Jamaati, H ; Salimi, A ; Raoufy, M. R ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Asthma is a chronic inflammatory disease associated with a high prevalence of psychiatric disorders. There are specific brain networks responsible for emotional processes, including two important networks associated with psychiatric problems: the default mode network (DMN), which is more active in the resting state, and the salience network (SN), which is structurally connected to DMN. Although previous studies suggested that neuro-phenotypes of asthma may be recognizable by the neural activity of brain circuits, an association between the brain's functional alterations and psychiatric impairments induced by asthma remains unknown. We aimed to assess DMN and SN activity and its association...
Graphene-based nanomaterials in fighting the most challenging viruses and immunogenic disorders
, Article ACS Biomaterials Science and Engineering ; Volume 8, Issue 1 , 2022 , Pages 54-81 ; 23739878 (ISSN) ; Asadi, M ; Akhavan, O ; Sharif University of Technology
American Chemical Society
2022
Abstract
Viral diseases have long been among the biggest challenges for healthcare systems around the world. The recent Coronavirus Disease 2019 (COVID-19) pandemic is an example of how complicated the situation can get if we are not prepared to combat a viral outbreak in time, which brings up the need for quick and affordable biosensing platforms and vast knowledge of potential antiviral effects and drug/gene delivery opportunities. The same challenges have also existed for nonviral immunogenic disorders. Nanomedicine is considered a novel candidate for effectively overcoming these worldwide challenges. Among the versatile nanomaterials commonly used in biomedical applications, graphene has recently...