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    Computational study of geometric effects of bottom wall microgrooves on cell docking inside microfluidic devices

    , Article Journal of Mechanics in Medicine and Biology ; Volume 21, Issue 2 , 2021 ; 02195194 (ISSN) Ahandoust, S ; Saadatmand, M ; Sharif University of Technology
    World Scientific  2021
    Abstract
    Cells docking inside microfluidic devices is effective in studying cell biology, cell-based biosensing, as well as drug screening. Furthermore, single cell and regularly cells docking inside the microstructure of microfluidic systems are advantageous in different analyses of single cells exposed to equal drug concentration and mechanical stimulus. In this study, we investigated bottom wall microgrooves with semicircular and rectangular geometries with different sizes which are suitable for single cell docking along the length of the microgroove in x-direction and numerous cells docking regularly in one line inside the microgroove in a 3D microchannel. We used computational fluid dynamics to... 

    Computational study of geometric effects of bottom wall microgrooves on cell docking inside microfluidic devices

    , Article Journal of Mechanics in Medicine and Biology ; Volume 21, Issue 2 , 2021 ; 02195194 (ISSN) Ahandoust, S ; Saadatmand, M ; Sharif University of Technology
    World Scientific  2021
    Abstract
    Cells docking inside microfluidic devices is effective in studying cell biology, cell-based biosensing, as well as drug screening. Furthermore, single cell and regularly cells docking inside the microstructure of microfluidic systems are advantageous in different analyses of single cells exposed to equal drug concentration and mechanical stimulus. In this study, we investigated bottom wall microgrooves with semicircular and rectangular geometries with different sizes which are suitable for single cell docking along the length of the microgroove in x-direction and numerous cells docking regularly in one line inside the microgroove in a 3D microchannel. We used computational fluid dynamics to... 

    The influence of micro air jets on mixing augmentation of transverse hydrogen jet in supersonic flow

    , Article International Journal of Hydrogen Energy ; Volume 41, Issue 47 , 2016 , Pages 22497-22508 ; 03603199 (ISSN) Barzegar Gerdroodbary, M ; Mokhtari, M ; Fallah, K ; Pourmirzaagha, H ; Sharif University of Technology
    Elsevier Ltd  2016
    Abstract
    In this paper, numerical simulation is performed to investigate the effects of micro air jets on mixing of the micro hydrogen jet in a transverse supersonic flow. The fundamental flow feature of the interaction between an array of fuel and air jets is investigated in a Mach 4.0 crossflow with a fuel global equivalence ratio of 0.5. Parametric studies were conducted on the various air jet conditions by using the Reynolds-averaged Navier–Stokes equations with Menter's Shear Stress Transport (SST) turbulence model. Numerical study of eight streamwise transverse sonic fuel and air jets in a fully turbulent supersonic flow revealed an extremely complex feature of fuel and air jet interaction. The...