Sharif Digital Repository

DNA molecule is one of the most important macromolecules in cell, which carries genetic information for life. DNA is often in confined geometries, such as, packaging in cell and DNA-protein interactions. While DNA is nearly a stiff polymer, its elastic behaviour plays a crucial role on its functionalities.Therefore, investigating the elastic and mechanical properties of DNA is really important.The elastic behaviour of a long and free DNA can be predicted very accurately by ”worm-like chain“ (WLC) model. In WLC model, DNA is assumed as a elastic rod with harmonic potential of local bending and twist.Many structural properties of DNA have been ignored in this model. But in recent years, by...