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Evaluation of differentiation quality of several differentiation inducers of bone marrow-derived mesenchymal stem cells to nerve cells by as-sessing expression of beta-tubulin 3 marker: A systematic review
, Article Current Stem Cell Research and Therapy ; Volume 16, Issue 8 , 2021 , Pages 994-1004 ; 1574888X (ISSN) ; Zahedi, F ; Hashemi, Z. S ; Khalili, S ; Sharif University of Technology
Bentham Science Publishers
2021
Abstract
Neurological diseases have different etiological causes. Contemporary, developing an ef-fective treatment for these diseases is an ongoing challenge. Cell therapy is recognized as one of the promising solutions for the treatment of these diseases. Amongst various types of stem cells, bone marrow-derived mesenchymal stem cells (BM-MSC) are known to be the most widely used stem cells. These cells are endowed with appealing properties such as the ability to differentiate into other cell types, including the muscle, liver, glial, and nerve cells. In this review study, we have systematically evaluated the ability of a variety of chemical compounds used in the last ten years to differentiate...