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biomedical-coatings
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Fabrication mechanism of nanostructured HA/TNTs biomedical coatings: an improvement in nanomechanical and in vitro biological responses
, Article Journal of Materials Science: Materials in Medicine ; Volume 27, Issue 10 , 2016 ; 09574530 (ISSN) ; Riahi, Z ; Eslami, A ; Sadrnezhaad, S. K ; Sharif University of Technology
Springer New York LLC
2016
Abstract
In this paper, a mechanism for fabrication of nanostructured hydroxyapatite coating on TiO2 nanotubes is presented. Also, the physical, biological, and nanomechanical properties of the anodized Ti6Al4V alloy consisting TiO2 nanotubes, electrodeposited hydroxyapatite, and the hydroxyapatite/TiO2 nanotubes double layer coating on Ti6Al4V alloy implants are compared. Mean cell viability of the samples being 84.63 % for uncoated plate, 91.53 % for electrodeposited hydroxyapatite, and 94.98 % for hydroxyapatite/TiO2 nanotubes coated sample were in the acceptable range. Merely anodized prototype had the highest biocompatibility of 110 % with respect to the control sample. Bonding strength of...
In vitro bioactivity and biocompatibility of magnesium implants coated with poly(methyl methacrylate) - bioactive glass composite
, Article Materials Today Communications ; Volume 33 , 2022 ; 23524928 (ISSN) ; Jafari, H ; Pishbin, F ; Mohandes, F ; Simchi, A ; Sharif University of Technology
Elsevier Ltd
2022
Abstract
Magnesium (Mg) and its alloys have proved promising as biodegradable candidates for the repair of bone tissue. Despite the encouraging bio-related properties of Mg, its high corrosion rate in contact with body fluids still presents a major challenge. An efficient approach to address this issue is to provide a protective coating on Mg. The present research evaluates, for the first time, in vitro bioactivity and biocompatibility of a novel multifunctional composite coating based on poly(methyl methacrylate) (PMMA) biopolymer and bioactive glass (BG) particles on Mg-based implant. Electrophoretic deposition (EPD) was utilized to obtain this coating from a bi-component suspension. Coatings’...
Bioinspired TiO2/chitosan/HA coatings on Ti surfaces: Biomedical improvement by intermediate hierarchical films
, Article Biomedical Materials (Bristol) ; Volume 17, Issue 3 , 2022 ; 17486041 (ISSN) ; Ahmadi Seyedkhani, S ; Eslami Saed, A ; Sadrnezhaad, S. K ; Seza, A ; Sharif University of Technology
Institute of Physics
2022
Abstract
The most common reasons for hard-tissue implant failure are structural loosening and prosthetic infections. Hence, in this study, to overcome the first problem, different bioinspired coatings, including dual acid-etched, anodic TiO2 nanotubes array, anodic hierarchical titanium oxide (HO), micro- and nanostructured hydroxyapatite (HA) layers, and HA/chitosan (HA/CS) nanocomposite, were applied to the titanium alloy surfaces. X-ray diffraction and FTIR analysis demonstrated that the in situ HA/CS nanocomposite formed successfully. The MTT assay showed that all samples had excellent cell viability, with cell proliferation rates ranging from 120% to 150% after 10 days. The HO coating...