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Metal–organic frameworks (MOFs) for cancer therapy
, Article Materials ; Volume 14, Issue 23 , 2021 ; 19961944 (ISSN) ; Rabiee, N ; Mozafari, M ; Verpoort, F ; Voskressensky, L. G ; Luque, R ; Sharif University of Technology
MDPI
2021
Abstract
MOFs exhibit inherent extraordinary features for diverse applications ranging from cataly-sis, storage, and optics to chemosensory and biomedical science and technology. Several procedures including solvothermal, hydrothermal, mechanochemical, electrochemical, and ultrasound techniques have been used to synthesize MOFs with tailored features. A continued attempt has also been directed towards functionalizing MOFs via “post-synthetic modification” mainly by changing linkers (by altering the type, length, functionality, and charge of the linkers) or node components within the MOF framework. Additionally, efforts are aimed towards manipulating the size and morphology of crystallite domains in...
Synthesis, properties and biomedical applications of carbon-based quantum dots: an updated review
, Article Biomedicine and Pharmacotherapy ; Volume 87 , 2017 , Pages 209-222 ; 07533322 (ISSN) ; Negahdari, B ; Eatemadi, A ; Sharif University of Technology
Elsevier Masson SAS
2017
Abstract
Carbon-based quantum dots (CQDs) are a newly developed class of carbon nano-materials that have attracted much interest and attention as promising competitors to already available semiconductor quantum dots owing to their un-comparable and unique properties. In addition, controllability of CQDs unique physiochemical properties is as a result of their surface passivation and functionalization. This is an update article (between 2013 and 2016) on the recent progress, characteristics and synthesis methods of CQDs and different advantages in varieties of applications. © 2017 Elsevier Masson SAS
Pyrolytic carbon coating for cytocompatibility of titanium oxide nanoparticles: A promising candidate for medical applications
, Article Nanotechnology ; Volume 23, Issue 4 , 2012 ; 09574484 (ISSN) ; Imani, M ; Yousefi, M ; Galinetto, P ; Simchi, A ; Amiri, H ; Stroeve, P ; Mahmoudi, M ; Sharif University of Technology
2012
Abstract
Nanoparticles for biomedical use must be cytocompatible with the biological environment that they are exposed to. Current research has focused on the surface functionalization of nanoparticles by using proteins, polymers, thiols and other organic compounds. Here we show that inorganic nanoparticles such as titanium oxide can be coated by pyrolytic carbon (PyC) and that the coating has cytocompatible properties. Pyrolization and condensation of methane formed a thin layer of pyrolytic carbon on the titanium oxide core. The formation of the PyC shell retards coalescence and sintering of the ceramic phase. Our MTT assay shows that the PyC-coated particles are cytocompatible at employed doses
Review on different experimental techniques developed for recording force-deformation behaviour of soft tissues; with a view to surgery simulation applications
, Article Journal of Medical Engineering and Technology ; Volume 41, Issue 4 , 2017 , Pages 257-274 ; 03091902 (ISSN) ; Rostami, M ; Farahmand, F ; Sharif University of Technology
Abstract
Different experimental techniques which have been developed to obtain data related to force-deformation behaviour of soft tissues play an important role in realistically simulating surgery processes as well as medical diagnoses and minimally invasive procedures. Indeed, an adequate quantitative description of soft-tissue-mechanical-behaviour requires high-quality experimental data to be obtained and analysed. In this review article we will first scan the motivations and basic technical issues on surgery simulation. Then, we will concentrate on different experimental techniques developed for recording force-deformation (stress-strain) behaviour of soft tissues with focussing on the in-vivo...
Preparation and characterization of multi-walled carbon nanotube/hydroxyapatite nanocomposite film dip coated on Ti-6Al-4V by sol-gel method for biomedical applications: An in vitro study
, Article Materials Science and Engineering C ; Volume 33, Issue 4 , 2013 , Pages 2002-2010 ; 09284931 (ISSN) ; Hooshmand, T ; Mohammadi, M ; Najafi, F ; Sharif University of Technology
2013
Abstract
In the present research, the introduction of multi-walled carbon nanotubes (MWCNTs) into the hydroxyapatite (HA) matrix and dip coating of nanocomposite on titanium alloy (Ti-6Al-4V) plate was conducted in order to improve the performance of the HA-coated implant via the sol-gel method. The structural characterization and electron microscopy results confirmed well crystallized HA-MWCNT coating and homogenous dispersion of carbon nanotubes in the ceramic matrix at temperatures as low as 500 C. The evaluation of the mechanical properties of HA and HA/MWCNT composite coatings with different weight percentages of MWCNTs showed that the addition of low concentrations of MWCNTs (0.5 and 1 wt.%)...
Biosynthesis of copper oxide nanoparticles with potential biomedical applications
, Article International Journal of Nanomedicine ; Volume 15 , 2020 , Pages 3983-3999 ; Bagherzadeh, M ; Kiani, M ; Ghadiri, A. M ; Etessamifar, F ; Jaberizadeh, A. H ; Shakeri, A ; Sharif University of Technology
Dove Medical Press Ltd
2020
Abstract
Introduction: In recent years, the use of cost-effective, multifunctional, environmentally friendly and simple prepared nanomaterials/nanoparticles have been emerged considerably. In this manner, different synthesizing methods were reported and optimized, but there is still lack of a comprehensive method with multifunctional properties. Materials and Methods: In this study, we aim to synthesis the copper oxide nanoparticles using Achillea millefolium leaf extracts for the first time. Catalytic activity was investigated by in situ azide alkyne cycloaddition click and also A3 coupling reaction, and optimized in terms of temperature, solvent, and time of the reaction. Furthermore, the...