Sharif Digital Repository

Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of soft materials is done using light tweezers. This work investigates micrometer particle movements in the optical trap and also, when they are connected to a red blood cell. The tweezers allow the Newtonian fluid viscosity, such as water and glycerin, to measure the mechanical properties of viscoelastic... 

Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of soft materials is done using light tweezers. This work investigates micrometer particle movements in the optical trap and also, when they are connected to a red blood cell. The tweezers allow the Newtonian fluid viscosity, such as water and glycerin, to measure the mechanical properties of viscoelastic... 

Cardiovascular diseases are one of the major causes of death in the world; atherosclerosis being one aspect. Carotid bifurcation is one of the sites that are vulnerable to this disease. Wall Shear Stress (WSS) is known to be responsible for the process of atherogenesis. In this study, we have simulated the blood flow for Newtonian and non-Newtonian, steady and unsteady, flow conditions in three idealistic and five realistic geometries. A risk factor has been presented based on the results of wall shear stress and, then, a relation was found between geometrical features and the wall shear stress risk factor. Our main conclusions are: 1) The non-Newtonian behavior of blood elevates the value...