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    Numerical simulation of unsteady airflow in a nasal cavity for various sizes of maxillary sinus opening in a virtual endoscopic surgery

    , Article Respiratory Physiology and Neurobiology ; Volume 291 , 2021 ; 15699048 (ISSN) Moniripiri, M ; Amjadimanesh, H ; Faramarzi, M ; Sadrizadeh, S ; Abouali, O ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    Functional endoscopic sinus surgery (FESS) is performed to treat sinusitis when treatment with medication fails. In the present study, three different virtual maxillary sinus endoscopic surgeries were performed on a realistic 3-D computational model of the nasal cavity of an adult male under the supervision of a specialist. They included only uncinectomy, uncinectomy + 8mm Middle Meatal Antrostomy (MMA) and uncinectomy + 18 mm MMA. Simulations were performed for two human activity respiratory rates, including rest and moderate activities, and effects of different surgeries and respiratory rates on maxillary sinus were investigated. It was found that after endoscopic sinus surgery, the volume... 

    Classification of asthma based on nonlinear analysis of breathing pattern

    , Article PLoS ONE ; Volume 11, Issue 1 , 2016 ; 19326203 (ISSN) Raoufy, M. R ; Ghafari, T ; Darooei, R ; Nazari, M ; Mahdaviani, S. A ; Eslaminejad, A. R ; Almasnia, M ; Gharibzadeh, S ; Mani, A. R ; Hajizadeh, S ; Sharif University of Technology
    Public Library of Science  2016
    Abstract
    Normal human breathing exhibits complex variability in both respiratory rhythm and volume. Analyzing such nonlinear fluctuations may provide clinically relevant information in patients with complex illnesses such as asthma. We compared the cycle-by-cycle fluctuations of inter-breath interval (IBI) and lung volume (LV) among healthy volunteers and patients with various types of asthma. Continuous respiratory datasets were collected from forty agematched men including 10 healthy volunteers, 10 patients with controlled atopic asthma, 10 patients with uncontrolled atopic asthma, and 10 patients with uncontrolled non-atopic asthma during 60 min spontaneous breathing. Complexity of breathing... 

    Computational simulation of temperature and velocity distribution in human upper respiratory airway during inhalation of hot air

    , Article Respiratory Physiology and Neurobiology ; Volume 223 , 2016 , Pages 49-58 ; 15699048 (ISSN) Goodarzi Ardakani, V ; Taeibi Rahni, M ; Salimi, M. R ; Ahmadi, G ; Sharif University of Technology
    Elsevier  2016
    Abstract
    The present study provides an accurate simulation of velocity and temperature distributions of inhalation thermal injury in a human upper airway, including vestibule, nasal cavity, paranasal sinuses, nasopharynx, oropharynx, larynx, and upper part of main bronchus. To this end, a series of CT scan images, taken from an adult woman, was used to construct a three dimensional model. The airway walls temperature was adjusted according to existing in vivo temperature measurements. Also, in order to cover all breathing activities, five different breathing flow rates (10, 15, 20, 30, and 40. l/min) and different ambient air temperatures (100, 200, 300, 400, and 500. °C) were studied. Different flow...