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cardiorespiratory-system
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Unified Modeling and Simulation of Cardio-Pulmonary System in Human Body to Mimic Central Nervous System Behavior to Control the Oxygen & CO2 Levels in this System
, M.Sc. Thesis Sharif University of Technology ; Bozorgmehry Boozarjomehry, Ramin (Supervisor)
Abstract
A mathematical model helps to understand any system with any level of complication, such as the human body. The heart, vascular system, and lungs are three important parts of each body that life is impossible without them. The performance of the cardiovascular and respiratory systems is tuned by a group of complex mechanisms which are called regulatory mechanisms. Therefore, a model which describes the behavior of these mechanisms has great importance. The goal of this research is to provide and simulate the newest and most complete model in this field. The presented model should consist of the heart, vascular system, lungs, respiratory system, gas exchange and transport, and finally...
Mathematical modeling of heart rate and blood pressure variations due to changes in breathing pattern
, Article 2013 20th Iranian Conference on Biomedical Engineering, ICBME 2013, Tehran, 18 December 2013 through 20 December 2013 ; 2013 , Pages 54-58 ; Zahedi, E ; Sharif University of Technology
IEEE Computer Society
2013
Abstract
Analysis of the heart rate (HR) variation due to respiration, known as respiratory sinus arrhythmia (RSA), is a method to assess the autonomic nervous system (ANS) function. In this paper a physiologically-based mathematical model consisting of the cardiorespiratory system and ANS control has been used in order to study the cardiovascular response (mean arterial blood pressure and HR) to breathing with different respiration rates and tidal volumes. Simulation results show that RSA has its maximal amplitude at the respiration frequency of 0.12 Hz and that RSA amplitude varies linearly by tidal volume. These results are in agreement with real data from the literature. In addition, the...