Search for: carotid-artery-bifurcation
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    Multidimensional modeling of the stenosed carotid artery: A novel CAD approach accompanied by an extensive lumped model

    , Article Acta Mechanica Sinica/Lixue Xuebao ; Vol. 30, issue. 2 , 2014 , p. 259-273 Kashefi, A ; Mahdinia, M ; Firoozabadi, B ; Amirkhosravi, M ; Ahmadi, G ; Saidi, M. S ; Sharif University of Technology
    This study describes a multidimensional 3D/lumped parameter (LP) model which contains appropriate inflow/outflow boundary conditions in order to model the entire human arterial trees. A new extensive LP model of the entire arterial network (48 arteries) was developed including the effect of vessel diameter tapering and the parameterization of resistance, conductor and inductor variables. A computer aided-design (CAD) algorithm was proposed to efficiently handle the coupling of two or more 3D models with the LP model, and substantially lessen the coupling processing time. Realistic boundary conditions and Navier-Stokes equations in healthy and stenosed models of carotid artery bifurcation... 

    Multi-layered nature of the wall of the carotid-artery bifurcation on hemodynamic and mechanical stress and strain

    , Article 2011 18th Iranian Conference of Biomedical Engineering, ICBME 2011 ; 2011 , Pages 84-89 ; 9781467310055 (ISBN) Nikparto, A ; Firoozabadi, B. D ; Sharif University of Technology
    Arterial diseases, namely atherosclerosis, are believed to be a product of abnormal changes in both hemodynamic and non-hemodynamic factors. In order to explornmk,e the role of different factors in initiation and progression of this disease, a CFD technique was applied to study Interaction between the structure of the artery and blood flow for different suggested models that were used to describe mechanics of vessel wall. This study presents a three-dimensional, steady state simulation of blood flow through the single and double layered carotid artery bifurcation using fluid structure interaction (FSI) method. The wall shear stress and mechanical stress/strain are computed and analyzed under... 

    Numerical simulations of haemodynamic factors and hyperelastic Circumferential Strain/Stress in the ideal and healthy-patient-specific carotid bifurcations for different rheological models

    , Article International Journal of Biomedical Engineering and Technology ; Volume 6, Issue 4 , 2011 , Pages 387-412 ; 17526418 (ISSN) Toloui, M ; Nikparto, A ; Firoozabadi, B ; Saidi, M. S ; Sharif University of Technology
    To explore the role of hemodynamic in the initiation and progression of stenosis in carotid artery bifurcation, a Computational Fluid Dynamics (CFD) technique is applied. The effect of four rheology models is investigated as well as various mechanical phenomena. In this study, a Finite Element Method (FEM) was applied to simulate the physiologic Circumferential Strain/Stress (CS) Meanwhile, to investigate the role of vessel wall flexibility, a Fluid-Structure Interaction (FSI) analysis was applied. It was concluded that velocity profiles and WSS show sensitivity to arterial wall stiffening while shear thinning models do not have a dominant effect on the flow field  

    Atheroprone sites of coronary artery bifurcation: Effect of heart motion on hemodynamics-dependent monocytes deposition

    , Article Computers in Biology and Medicine ; Volume 133 , 2021 ; 00104825 (ISSN) Biglarian, M ; Firoozabadi, B ; Saidi, M. S ; Sharif University of Technology
    Elsevier Ltd  2021
    Atherosclerosis as a common cardiovascular disease is a result of both adverse hemodynamics conditions and monocyte deposition within coronary arteries. It is known that the adhesion of monocytes on the arterial wall and their interaction with the vascular surface are one of the main parameters in the initiation and progression of atherosclerosis. In this work, hemodynamic parameters and monocyte deposition have been investigated in a 3D computational model of the Left Anterior Descending coronary artery (LAD) and its first diagonal branch (D1) under the heart motion. A one-way Lagrangian approach is performed to trace the monocyte particles under different blood flow regimes and heart motion...