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    Fundamental limit for gain and resolution in analog optical edge detection

    , Article Optics Express ; Volume 28, Issue 2 , 2020 , Pages 898-911 Karimi, P ; Khavasi, A ; Mousavi Khaleghi , S. S ; Sharif University of Technology
    OSA - The Optical Society  2020
    In this paper, the relation between gain and resolution of an ideal analog optical differentiator in two different cases and their fundamental limits are investigated. Based on this relation, a figure of merit for comparison of the designed differentiators in recent papers is proposed. The differentiators are optimized using this figure of merit, and they are compared with each other to determine the best one. Also, a new differentiator is presented based on the dielectric slab waveguide in which the trade-off between its gain and resolution is easily controllable, and its best operating point is determined. © 2020 Optical Society of America under the terms of the OSA Open Access Publishing... 

    Design and fabrication of a new expandable transtibial liner with manual volume control: A prototype

    , Article Journal of Biomedical Physics and Engineering ; Volume 10, Issue 4 , 2020 , Pages 543-548 Nouri, M. J ; Aminian, G ; Farahmand, F ; Rahgozar, M ; Sharif University of Technology
    Shiraz University of Medical Sciences  2020
    Diurnal volume changes is one of the main factors influencing socket fit in trans-tibial prosthesis and causing pressure problem issues. Embedded bladder liners have been recently a potential approach to deal with this problem. The aim of this technical note was to introduce a new transtibial silicone liner designed based on hybrid socket theory. To make expandability in the liner, an integrated wax structure was constructed over the selected areas of the positive model and then removed after lamination process. In addition, a mechanical system with manual control was designed to fit the liner with the residual limb volume by pumping the water in or out of the liner through connec-tive... 

    Design and evaluation of an articulated ankle foot orthosis with plantarflexion resistance on the gait: A case series of 2 patients with hemiplegia

    , Article Journal of Biomedical Physics and Engineering ; Volume 10, Issue 1 , 2020 , Pages 119-128 Daryabor, A ; Arazpour, M ; Aminian, G ; Baniasad, M ; Yamamoto, S ; Sharif University of Technology
    Shiraz University of Medical Sciences  2020
    Ankle-foot orthoses (AFOs) have been described to have positive effects on the gait biomechanics in stroke patients. The plantarflexion resistance of an AFO is considered important for hemiplegic patients, but the evidence is still limited. The purpose of this case series was to design and evaluate the immediate effect of an articulated AFO on kinematics and kinetics of lower-limb joints in stroke patients. The articulated AFO with the adjustment of plantarflexion resistance was designed. The spring generates a plantarflexion resistance of the ankle joint at initial stance phase. The efficacy of orthosis was evaluated on two stroke patients in 2 conditions: without an AFO and with the AFO.... 

    Wrist-RoboHab: A robot for treatment and evaluation of brain injury patients

    , Article IEEE International Conference on Rehabilitation Robotics, 27 June 2011 through 1 July 2011, Zurich ; 2011 ; 19457898 (ISSN) ; 9781424498628 (ISBN) Baniasad, M. A ; Farahmand, F ; Ansari, N. N ; Sharif University of Technology
    This article, introduces a new haptic robot, wrist-RoboHab, for upper limb rehabilitation of post stroke, orthopedic and Parkinson patients., The robot is designed for hand movement therapy and could be used for both treatment and evaluation purposes in three operational states; forearm supination/pronation, wrist flexion/extension and ulnar/radial deviation. At first the mechanical design and control system are described. Then the results of a case study are demonstrated. Clinical results, showed an improvement in Fugle-Meyer, AROM, power and the biomechanical assessment of the spasticity in a chronic patient. Furthermore, it was approved that the robot can have a good interaction with... 

    The influence of new reciprocating link medial linkage orthosis on walking and independence in a spinal cord injury patient

    , Article Spinal Cord ; Volume 53 , October , 2015 , Pages S10-S12 ; 13624393 (ISSN) Ahmadi Bani, M ; Arazpour, M ; Farahmand, F ; Azmand, A ; Hutchins, S. W ; Vahab Kashani, R ; Mousavi, M. E ; Sharif University of Technology
    Nature Publishing Group  2015
    Objectives: The purpose of this paper is to describe the development and evaluation of a new medial linkage reciprocating gait orthosis (MLRGO) that incorporates a reciprocal mechanism and is sensitive to pelvic motion to potentially assist paraplegic patients to walk and provide functional independence. Case description and methods: The new orthosis was constructed and tested by a 20-year-old female paraplegic subject with transverse myelitis at T10 level, who was 4 years post injury and had also been an isocentric reciprocating gait orthosis (IRGO) user for 2 years. She received gait training for 12 weeks before undertaking gait analysis, and also completed a questionnaire that was... 

    P 134 – Absence of the patella has minimal effects on sagittal plane gait parameters

    , Article Gait and Posture ; Volume 65 , 2018 , Pages 462-464 ; 09666362 (ISSN) Baghdadi, S ; Khandan, A ; Arab Baniasad, M ; Darbandi, H ; Vafaei, A. R ; Sharif University of Technology
    Elsevier B.V  2018
    Patella is the latest addition to the animal's skeleton. It's role in normal walking has not been clearly defined. A 9-year-old girl with congenital absence of the patella was assessed using instrumented gait analysis. The results show a tendency for the limb for external rotation, which is more pronounced during swing. We suggest that the role of the patella is mainly to redirect the force of the quadriceps tendon medially. The classically described role, which is to increase the lever arm of the quadriceps tendon, was not confirmed in this study. © 2018 Elsevier B.V  

    Role and significance of trunk and upper extremity muscles in walker-assisted paraplegic gait: a case study

    , Article Topics in Spinal Cord Injury Rehabilitation ; Volume 24, Issue 1 , 2018 , Pages 18-27 ; 10820744 (ISSN) Baniasad, M ; Farahmand, F ; Arazpour, M ; Zohoor, H ; Sharif University of Technology
    Thomas Land Publishers Inc  2018
    Background and Purpose: Understanding the role and significance of trunk and upper extremity muscles in paraplegic gait can help in designing more effective assistive devices for these patients and also provides valuable information for improving muscle strengthening programs. Methods: In a patient with a spinal cord injury (SCI) who could walk independently (rating scale of ambulatory capacity, 9) with the aid of bilateral ankle-foot orthosis and a walker, the kinematics, kinetics and electromyographic (EMG) activities of 16 muscles from the trunk and upper and lower extremities were recorded during gait. The onset, cessation, and duration of the EMG signal were associated with the 4 phases... 

    Studying the effect of kinematical pattern on the mechanical performance of paraplegic gait with reciprocating orthosis

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 226, Issue 8 , 2012 , Pages 600-611 ; 09544119 (ISSN) Nakhaee, K ; Farahmand, F ; Salarieh, H ; Sharif University of Technology
    SAGE  2012
    Paraplegic users of mechanical walking orthoses, e.g. advanced reciprocating gait orthosis (ARGO), often face high energy expenditure and extreme upper body loading during locomotion. We studied the effect of kinematical pattern on the mechanical performance of paraplegic locomotion, in search for an improved gait pattern that leads to lower muscular efforts. A three-dimensional, four segment, six-degrees-of-freedom skeletal model of the advanced reciprocating gait orthosis-assisted paraplegic locomotion was developed based on the data acquired from an experimental study on a single subject. The effect of muscles was represented by ideal joint torque generators. A response surface analysis... 

    Mathematical modeling of CSF pulsatile hydrodynamics based on fluid-solid interaction

    , Article IEEE Transactions on Biomedical Engineering ; Volume 57, Issue 6 , 2010 , Pages 1255-1263 ; 00189294 (ISSN) Masoumi, N ; Bastani, D ; Najarian, S ; Ganji, F ; Farmanzad, F ; Seddighi, A. S ; Sharif University of Technology
    Intracranial pressure (ICP) is derived from cerebral blood pressure and cerebrospinal fluid (CSF) circulatory dynamics and can be affected in the course of many diseases. Computer analysis of the ICP time pattern plays a crucial role in the diagnosis and treatment of those diseases. This study proposes the application of Linninger et al.s [IEEE Trans. Biomed. Eng. , vol. 52, no. 4, pp. 557565, Apr. 2005] fluidsolid interaction model of CSF hydrodynamic in ventricular system based on our clinical data from a group of patients with brain parenchyma tumor. The clinical experiments include the arterial blood pressure (ABP), venous blood pressure, and ICP in the subarachnoid space (SAS). These... 

    Combining multivariate image analysis with high-performance thin-layer chromatography for development of a reliable tool for saffron authentication and adulteration detection

    , Article Journal of Chromatography A ; Volume 1628 , 2020 Amirvaresi, A ; Rashidi, M ; Kamyar, M ; Amirahmadi, M ; Daraei, B ; Parastar, H ; Sharif University of Technology
    Elsevier B.V  2020
    In this work, high-performance thin-layer chromatography (HPTLC) coupled with multivariate image analysis (MIA) is proposed as a fast and reliable tool for authentication and adulteration detection of Iranian saffron samples based on their HPTLC fingerprints. At first, the secondary metabolites of saffron were extracted using ultrasonic-assisted solvent extraction (UASE) which was optimized using central composite design (CCD). Next, the RGB coordinates of HPTLC images were used for estimation of saffron origin based on principal component analysis (PCA). The PCA scores plot showed that saffron samples were clustered into two clear-cut groups which was 92% matched with the geographical... 

    A novel metabolic disorder in the degradation pathway of endogenous methanol due to a mutation in the gene of alcohol dehydrogenase

    , Article Clinical Biochemistry ; Volume 90 , 2021 , Pages 66-72 ; 00099120 (ISSN) Razzaghy Azar, M ; Nourbakhsh, M ; Vafadar, M ; Nourbakhsh, M ; Talebi, S ; Sharifi Zarchi, A ; Salehi Siavashani, E ; Garshasbi, M ; Sharif University of Technology
    Elsevier Inc  2021
    Background: A small amount of methanol is produced endogenously in the human body but it is efficiently metabolized by alcohol dehydrogenase (ADH) and other enzymes, and the products eliminated without harm. In this study, we present a new entity of inborn error of methanol metabolism due to a mutation in the ADH1C gene coding for the γ subunit that is part of several ADH isoenzymes. Results: This disorder was discovered in an 11.58-year-old boy. During one 9-month hospital admission, he had periods of 1–4 days during which he was comatose, and between these periods he was sometimes verbose and euphoric, and had ataxia, dysarthria. Following hemodialysis treatments, he became conscious and... 

    A detailed and validated three dimensional dynamic model of the patellofemoral joint

    , Article Journal of Biomechanical Engineering ; Volume 134, Issue 4 , 2012 ; 01480731 (ISSN) Akbar, M ; Farahmand, F ; Jafari, A ; Foumani, M. S ; Sharif University of Technology
    A detailed 3D anatomical model of the patellofemoral joint was developed to study the tracking, force, contact and stability characteristics of the joint. The quadriceps was considered to include six components represented by 15 force vectors. The patellar tendon was modeled using four bundles of viscoelastic tensile elements. Each of the lateral and medial retinaculum was modeled by a three-bundle nonlinear spring. The femur and patella were considered as rigid bodies with their articular cartilage layers represented by an isotropic viscoelastic material. The geometrical and tracking data needed for model simulation, as well as validation of its results, were obtained from an in vivo...