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    Numerical investigation of Antegrade Flow effects on fl ow pulsations in Fontan operation

    , Article International Journal of Biomedical Engineering and Technology ; Volume 10, Issue 3 , 2012 , Pages 221-238 ; 17526418 (ISSN) Ghoreyshi, M ; Saidi, M. S ; Navabi, M. A ; Firoozabadi, B. D ; Shabanian, R ; Sharif University of Technology
    2012
    Abstract
    This study considers blood fl ow in Total Cavopulmonary Connection (TCPC) morphology, created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood fl ow pulsatility; because of right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea stating that keeping Main Pulmonary Artery (MPA) partially open, would increase pulmonary fl ow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary fl ow pulsations, by means of Computational Fluid... 

    Pulsatile blood flow in total cavopulmonary connection: a comparison between Y-shaped and T-shaped geometry

    , Article Medical and Biological Engineering and Computing ; Volume 55, Issue 2 , 2017 , Pages 213-224 ; 01400118 (ISSN) Rajabzadeh Oghaz, H ; Firoozabadi, B ; Saidi, M. S ; Monjezi, M ; Navabi Shirazi, M. A ; Malakan Rad, E ; Sharif University of Technology
    Springer Verlag  2017
    Abstract
    Single-ventricle anomaly is a hereditary heart disease that is characterized by anatomical malformations. The main consequence of this malformation is desaturated blood flow, which without proper treatment increases the risk of death. The classical treatment is based on a three-stage palliative procedure which should begin from the first few days of patient’s life. The final stage is known as Fontan procedure, in which inferior vena cava is directly connected to pulmonary arteries without going through the ventricle. This connection is called total cavopulmonary connection (TCPC). After surgery, the single ventricle supplies adequate and saturated systemic blood flow to the body; however,... 

    Pulsating Pulmonary Blood Inflow in Total Cavopulmonary Connection (TCPC) after Fontan Surgery

    , M.Sc. Thesis Sharif University of Technology Moradi, Hamed (Author) ; Sayadi, Hassan (Supervisor) ; Firoozabadi, Bahar (Supervisor) ; Navabi Shirazi, Mohammad Ali (Co-Supervisor) ; Malakan Rad, Elaheh (Co-Supervisor)
    Abstract
    Patients with a single ventricle disease who have undergone Fontan surgery have always had long-term complications. These complications include pulmonary artery stiffness and decreased ability to exercise. In fact, due to removal of the right ventricle from the circulatory system, blood pressure and pulsatility inflow to total cavopulmonary connection (TCPC) are reduced following this surgery. Creating waves (radial displacement) on the IVC (Inferior Vena Cava) wall can increase pulmonary flow pulsations. The Objective of this study is to test the effect of induced wave amplitude on the pulmonary flow pulsations at the rest condition. Computational fluid dynamic (CFD) simulations were... 

    3D-1D simulation of flow in fontan operation: effects of antegrade flow on flow pulsations

    , Article Scientia Iranica ; Vol. 21, issue. 4 , 2014 , pp. 1378-1389 ; ISSN: 10263098 Monjezi, M ; Ghoreyshi, S. M ; Saidi, M. S ; Navabi, M. A ; Firoozabad, B. D ; Sharif University of Technology
    Abstract
    This study considers blood flow in total cavopulmonary connection (TCPC) morphology created in Fontan surgical procedure in patients with a single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility since the right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea of increasing pulmonary flow pulsations by keeping Main Pulmonary Artery (MPA) partially open while it was closed in ordinary TCPC operation. The purpose of the present study is to verify the effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations. The 3D geometry is reconstructed from CT... 

    Numerical modeling of pulsating inflow to the pulmonary arteries in TCPC morphology using FSI approach

    , Article ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE) ; Volume 3 A , 2013 ; 9780791856215 (ISBN) Rajabzadeh, H. R ; Firoozabadi, B ; Saidi, M. S ; Sohrabi, S ; Mehr, S. M. N ; Sharif University of Technology
    2013
    Abstract
    The Fontan surgery is performed on patients with a single ventricle heart defect to prevent the combination of highlyoxygenated and poorly-oxygenated blood. Blood flow in total cavopulmonary connection (TCPC) which culminates an ordinary Fontan operation is practically steady-state but this flow is not appropriate for respiratory systems. This article investigates an approach in Fontan surgery that has been recently proposed in order to make the pulmonary blood flow pulsating. Moreover, for investigating the compliance of vessels and its effects on blood flow in TCPC, we have used the FSI (Fluid Structure Interaction) method as well as rigid wall assumption for comparison purposes. Our TCPC... 

    Generating a Pulsatile Pulmonary Flow after Fontan Operation by Means of Computational Fluid Dynamics (CFD)

    , M.Sc. Thesis Sharif University of Technology Ghoreyshi, Mostafa (Author) ; Saidi, Mohamad Said (Supervisor) ; Firoozabadi, Bahar (Supervisor) ; Navaee Shirazei, Mohammad Ali (Co-Advisor)
    Abstract
    This study considers blood flow in total cavopulmonary connection (TCPC) morphology, which is created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces the pulmonary blood flow pulsatility; because of right ventricle being bypassed. This phenomenon causes a lot of side effects for patients. A cardiac surgeon has suggested that keeping main pulmonary artery (MPA) partially open, would increase pulmonary flow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify the effects of keeping MPA partially open on pulmonary flow pulsations, by means of computational fluid dynamics (CFD)....