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    Fabrication and Characterization of Anode Supported Micro-tubular Solid Oxide Fuel Cells Prepared by Successive Non-aqueous Electrophoretic Deposition

    , M.Sc. Thesis Sharif University of Technology Keshavarz, Mitra (Author) ; Nemati, Ali (Supervisor) ; Paydar, Mohammad Hossein (Supervisor)
    The commercial breakthrough of micro-tubular solid oxide fuel cells (MT-SOFCs) is still facing so many challenges because of the complexity of their manufacturing process and the high cost associated with them. By deploying electrophoretic deposition as a simple and cost-effective method, the different components of the fuel cells (the anode, electrolyte, and cathode) can deposit on the graphite rod as a sacrificial substrate. The next step is eliminating the sacrificial substrate which will make hollow rods of cell components. The results of this study show that the use of a particular type of pencil lead will have a minimal negative impact on the overall fuel cell performance, leading to a... 

    Mechanical reinforcement of urinary bladder matrix by electrospun polycaprolactone nanofibers

    , Article Scientia Iranica ; Volume 24, Issue 6 , 2017 , Pages 3476-3480 ; 10263098 (ISSN) Ghafari, A. M ; Rajabi Zeleti, S ; Naji, M ; Ghanian, M. H ; Baharvand, H ; Sharif University of Technology
    For a successful repair and reconstruction of bladder tissue, fabrication of scaffolds with proper biochemical and biomechanical characteristics is necessary. Decellularized bladder tissue has been proposed in previous studies as a gold standard material for scaffold fabrication. However, weak mechanical properties of such a load-bearing tissue has remained a challenge. Incorporation of both biological and synthetic materials has been known as an effective strategy for improving mechanical and biological properties of the scaffolds. In the present work, a simple process was developed to fabricate hybrid hydrogel scaffolds with a biomimetic architecture from the natural urinary bladder... 

    Developmental barcoding of whole mouse via homing CRISPR

    , Article Science ; Volume 361, Issue 6405 , 2018 ; 00368075 (ISSN) Kalhor, R ; Kalhor, K ; Mejia, L ; Leeper, K ; Graveline, A ; Mali, P ; Church, G. M ; Sharif University of Technology

    Bacterial components as naturally inspired nano-carriers for drug/gene delivery and immunization: set the bugs to work?

    , Article Biotechnology Advances ; Volume 36, Issue 4 , 2018 , Pages 968-985 ; 07349750 (ISSN) Farjadian, F ; Moghoofei, M ; Mirkiani, S ; Ghasemi, A ; Rabiee, N ; Hadifar, S ; Beyzavi, A ; Karimi, M ; Hamblin, M. R ; Sharif University of Technology
    Elsevier Inc  2018
    Drug delivery is a rapidly growing area of research motivated by the nanotechnology revolution, the ideal of personalized medicine, and the desire to reduce the side effects of toxic anti-cancer drugs. Amongst a bewildering array of different nanostructures and nanocarriers, those examples that are fundamentally bio-inspired and derived from natural sources are particularly preferred. Delivery of vaccines is also an active area of research in this field. Bacterial cells and their components that have been used for drug delivery, include the crystalline cell-surface layer known as “S-layer” bacterial ghosts, bacterial outer membrane vesicles, and bacterial products or derivatives (e.g.... 

    Effect of Cu2+ ion on biological performance of nanostructured uorapatite doped with copper

    , Article Scientia Iranica ; Volume 24, Issue 6 , 2017 , Pages 2845-2855 ; 10263098 (ISSN) Nikonam Mofrad, R ; Sadrnezhaad, S. K ; Vahdati Khaki, J ; Sharif University of Technology
    Nanostructured copper-doped uorapatite (Cux.Ca(10X).(PO4)6.F2) having crystallite sizes of 19, 29, and 34 nm at x = 0:9, 0.4, and 0.0, respectively, was synthesized by planetary ball milling of CaO, P2O5, CaF2, and CuO powders. Specifications of the products were determined by Fourier-transform infrared spectroscopy, eld emission scanning electron microscopy, transmission electron microscopy, and X-ray di raction analyses. In-vitro studies and Mossman's Tetrazole Test (MTT) assays were also conducted by incubating Cux.Ca(10X).(PO6).F2 powder into Kokubo's Simulated Body Fluid (SBF) and against BT-20 cell, respectively, to determine bioactivity and biocompatibility of the materials.... 

    Biodiesel production from Spirulina microalgae feedstock using direct transesterification near supercritical methanol condition

    , Article Bioresource Technology ; Volume 239 , 2017 , Pages 378-386 ; 09608524 (ISSN) Mohamadzadeh Shirazi, H ; Karimi Sabet, J ; Ghotbi, C ; Sharif University of Technology
    Elsevier Ltd  2017
    Microalgae as a candidate for production of biodiesel, possesses a hard cell wall that prevents intracellular lipids leaving out from the cells. Direct or in situ supercritical transesterification has the potential for destruction of microalgae hard cell wall and conversion of extracted lipids to biodiesel that consequently reduces the total energy consumption. Response surface methodology combined with central composite design was applied to investigate process parameters including: Temperature, Time, Methanol-to-dry algae, Hexane-to-dry algae, and Moisture content. Thirty-two experiments were designed and performed in a batch reactor, and biodiesel efficiency between 0.44% and 99.32% was...