Sharif Digital Repository

The main goal of this study is to investigate the effects of plaque structure on its stress distribution. Rupture of plaque causes cerebrovascular diseases which lead to high mortality rates all over the world. Computers are powerful tools to understand the mechanism of plaque rupture. In this study, 3D fluid structure interaction simulation is constructed in ABAQUS 6.13 to clarify the relation between stress distribution of plaque and its structure. A model of common carotid artery with distributed stenosis was chosen for the simulation. To investigate the effects of plaque structure on stress distribution, thickness of fibrous cap and lipid core size were varied in the stenosis.... 

Background. Temporary artery clipping facilitates safe cerebral aneurysm management, besides a risk for cerebral ischemia. We developed an artificial neural network (ANN) to predict the safe clipping time of temporary artery occlusion (TAO) during intracranial aneurysm surgery. Method. We devised a three-layer model to predict the safe clipping time for TAO. We considered age, the diameter of the right and left middle cerebral arteries (MCAs), the diameter of the right and left A1 segment of anterior cerebral arteries (ACAs), the diameter of the anterior communicating artery, mean velocity of flow at the right and left MCAs, and the mean velocity of flow at the right and left ACAs, as well...