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      Solubilities of acetaminophen in supercritical carbon dioxide with and without menthol cosolvent: Measurement and correlation

      , Article Scientia Iranica ; Volume 19, Issue 3 , June , 2012 , Pages 619-625 ; 10263098 (ISSN) Karimi Sabet, J ; Ghotbi, C ; Dorkoosh, F ; Striolo, A ; Sharif University of Technology
      2012
      Abstract
      The solubility of acetaminophen in SuperCritical-Carbon Dioxide (SC- CO 2) with and without menthol as a cosolvent was measured at various temperatures (313, 328 and 343) K, and within pressures ranging from (10 to 25) MPa. It should be stated that the cosolvent, menthol, has chiral isomers with different melting points. Therefore, the effects of both menthol (I) with a lower melting point and menthol (II) with a higher melting point, as cosolvents on the solubility of acetaminophen in SC- CO 2, were studied. The experimental data collected in this work were obtained using a static flow apparatus. The experiments were replicated at least three times and the data reported are the average of... 
    Total 1 records