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    Stability behavior of single-phase natural circulation loop

    , Article 2003 ASME International Mechanical Engineers Congress, Washington, DC, 15 November 2003 through 21 November 2003 ; 2003 , Pages 119-131 ; 0791837157 (ISBN); 9780791837153 (ISBN) Moussavian, S. K ; Misale, M ; D'Auria, F ; Salehi, M ; Sharif University of Technology
    American Society of Mechanical Engineers  2003
    Abstract
    The circulating fluid in natural circulation loops would absorb heat from the hot zone (source) and will transport it to the cold zone (sink) without using of any mechanical pumps or other devices. The fluid density differences in hot and cold zones would lead buoyancy force which is introduced as the body force for the loop. By introducing the one-dimensional conservation equations; mass, momentum and energy in the loop and applying the perturbation method, or linear stability theory, would help us to study the stability of the rectangular natural circulation loop. The conservation equations in transient form were solved using the finite difference method. The results obtained from the... 

    Laboratory-Scale Design and Evaluation of Polymer-Fiber Composite in Order to Control Lost Circulation In Drilling Fluid

    , M.Sc. Thesis Sharif University of Technology Abdollahi, Maryam (Author) ; Ghotbi, Cyrus (Supervisor) ; Jafari, Taraneh (Supervisor) ; Nasiri, Alireza ($item.subfieldsMap.e)
    Abstract
    During the over balanced drilling operation in high permeability or fractured formations, drilling fluid loss and in more severe occasions fluid lost occurs which causes many problems and dangers and delayed the drilling operation until it was repaired. On the one hand, because of the high value of this material, and on the other hand, due to the increase in rig/day costs resulting from lost circulation control, leads to a significant increase in drilling costs. In this research, polymer-fiber composites have been designed and manufactured using extrusion method and have been investigated as fluid lost control agent in the laboratory scale for the first time in Iran. The effective parameters... 

    Circulant matrix representation of PN-sequences with ideal autocorrelation property

    , Article IWCIT 2015 - Iran Workshop on Communication and Information Theory, 6 May 2015 through 7 May 2015 ; May , 2015 ; 9781479982356 (ISBN) Khojasteh, M. J ; Shoreh, M. H ; Salehi, J. A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2015
    Abstract
    In this paper, we investigate PN-sequences with ideal autocorrelation property and the consequences of this property on the number of +1s and -1s and run structure of sequences. We begin by discussing and surveying about the length of PN-sequences with ideal autocorrelation property. From our discussion and survey we introduce circulant matrix representation of PN-sequence. Through circulant matrix representation we obtain system of non-linear equations that lead to ideal autocorrelation property. Rewriting PN-sequence and its autocorrelation property in {0,1} leads to a definition based on Hamming weight and Hamming distance and hence we can easily prove some results on the PN-sequences... 

    Design and parameter study of integrated microfluidic platform for CTC isolation and enquiry; a numerical approach

    , Article Biosensors ; Volume 8, Issue 2 , 18 June , 2018 ; 20796374 (ISSN) Shamloo, A ; Ahmad, S ; Momeni, M ; Sharif University of Technology
    2018
    Abstract
    Being the second cause of mortality across the globe, there is now a persistent effort to establish new cancer medication and therapies. Any accomplishment in treating cancers entails the existence of accurate identification systems empowering the early diagnosis. Recent studies indicate CTCs’ potential in cancer prognosis as well as therapy monitoring. The chief shortcoming with CTCs is that they are exceedingly rare cells in their clinically relevant concentration. Here, we simulated a microfluidic construct devised for immunomagnetic separation of the particles of interest from the background cells. This separation unit is integrated with a mixer subunit. The mixer is envisioned for... 

    Spectral classification and multiplicative partitioning of constant-weight sequences based on circulant matrix representation of optical orthogonal codes [electronic resource]

    , Article IEEE Transactions on Information Theory ; 2010 vol. 56, no. 9 Alem-Karladani, M. M. (Mohammad M.) ; Salehi, Jawad A ; $item.subfieldsMap.a ; Sharif University Of Technology

    Novel approaches in cancer management with circulating tumor cell clusters

    , Article Journal of Science: Advanced Materials and Devices ; Volume 4, Issue 1 , 2019 , Pages 1-18 ; 24682284 (ISSN) Rostami, P ; Kashaninejad, N ; Moshksayan, K ; Saidi, M. S ; Firoozabadi, B ; Nguyen, N. T ; Sharif University of Technology
    Elsevier B.V  2019
    Abstract
    Tumor metastasis is responsible for the vast majority of cancer-associated morbidities and mortalities. Recent studies have disclosed the higher metastatic potential of circulating tumor cell (CTC) clusters than single CTCs. Despite long-term study on metastasis, the characterizations of its most potent cellular drivers, i.e., CTC clusters have only recently been investigated. The analysis of CTC clusters offers new intuitions into the mechanism of tumor metastasis and can lead to the development of cancer diagnosis and prognosis, drug screening, detection of gene mutations, and anti-metastatic therapeutics. In recent years, considerable attention has been dedicated to the development of... 

    Cohen–Macaulayness of two classes of circulant graphs

    , Article Journal of Algebraic Combinatorics ; 2020 Hoang, D. T ; Maimani, H. R ; Mousivand, A ; Pournaki, M. R ; Sharif University of Technology
    Springer  2020
    Abstract
    Let n be a positive integer and let Sn be the set of all nonnegative integers less than n which are relatively prime to n. In this paper, we discuss structural properties of circulant graphs generated by the Sn′s and their complements. In particular, we characterize when these graphs are well-covered, Cohen–Macaulay, Buchsbaum or Gorenstein. © 2020, Springer Science+Business Media, LLC, part of Springer Nature  

    State, institutional entrepreneurship and the creation of the biopharmaceutical industry in a developing country

    , Article Journal of Science and Technology Policy Management ; 2021 ; 20534620 (ISSN) Babaee, A ; Mashayekhi, A. N ; HamidiMotlagh, R ; Sharif University of Technology
    Emerald Group Holdings Ltd  2021
    Abstract
    Purpose: This study aims to explore the emergence and development of new industries, especially in the context of developing countries, by considering industry emergence and development as a large-scale institutional change or transition. Design/methodology/approach: The authors conducted an inductive case study research on the emergence of the biopharmaceutical industry in a developing country. The data on the emergence and development of Iran’s biopharmaceutical industry during 1990 and 2018 were collected through semi-structured interviews, participation in meetings, visits to companies and analysis of archival texts. The data analysis was an inductive and iterative process. Findings: In... 

    From black and white to yin and yang: exploring the management of tensions in social enterprises

    , Article Journal of Social Entrepreneurship ; 2021 ; 19420676 (ISSN) Sarhangi, R ; Mashayekhi, A. N ; Souzanchi Kashani, E ; Sharif University of Technology
    Routledge  2021
    Abstract
    Social enterprises are organisations comprised of two conflicting logics: social and commercial. However, simultaneous commitment to both logics often leads to tensions, making social enterprises fragile organisations at the risk of mission drift. The extant literature on hybridity highlights two important overall strategies–integration and differentiation - for managing tensions. However, integration or differentiation alone can create additional problems, which is especially true in the case of differentiation, creating a situation comparable to black and white, with a salient faultline and heated conflicts. In this inductive qualitative case study, responding to the recent call in the... 

    Cohen–Macaulayness of two classes of circulant graphs

    , Article Journal of Algebraic Combinatorics ; Volume 53, Issue 3 , September , 2021 , Pages 805-827 ; 09259899 (ISSN) Hoang, D. T ; Maimani, H. R ; Mousivand, A ; Pournaki, M. R ; Sharif University of Technology
    Springer  2021
    Abstract
    Let n be a positive integer and let Sn be the set of all nonnegative integers less than n which are relatively prime to n. In this paper, we discuss structural properties of circulant graphs generated by the Sn’s and their complements. In particular, we characterize when these graphs are well-covered, Cohen–Macaulay, Buchsbaum or Gorenstein. © 2020, Springer Science+Business Media, LLC, part of Springer Nature  

    State, institutional entrepreneurship and the creation of the biopharmaceutical industry in a developing country

    , Article Journal of Science and Technology Policy Management ; Volume 13, Issue 4 , 2022 , Pages 765-787 ; 20534620 (ISSN) Babaee, A ; Mashayekhi, A. N ; HamidiMotlagh, R ; Sharif University of Technology
    Emerald Publishing  2022
    Abstract
    Purpose: This study aims to explore the emergence and development of new industries, especially in the context of developing countries, by considering industry emergence and development as a large-scale institutional change or transition. Design/methodology/approach: The authors conducted an inductive case study research on the emergence of the biopharmaceutical industry in a developing country. The data on the emergence and development of Iran’s biopharmaceutical industry during 1990 and 2018 were collected through semi-structured interviews, participation in meetings, visits to companies and analysis of archival texts. The data analysis was an inductive and iterative process. Findings: In... 

    Designing and Engineering of Lost Circulation Materials for Different Lost Circulation Scenarios

    , M.Sc. Thesis Sharif University of Technology Karimi Rad, Mohammad Saeed (Author) ; Goodarznia, Iraj (Supervisor) ; Tahmasebi, Korosh (Co-Advisor) ; kalhor, Mojtaba (Co-Advisor)
    Abstract
    Nowadays, one of the most major problems in drilling industry is Lost Circulation in different formations. Lost Circulation increases non-productive time, expenditures and environmental damages. Lost Circulation can happen in natural or induced fractures, cavernous formations and high permeable rocks and it can be subcategorized in seepage, medium, severe or complete type based on the severity of the problem. For addressing this issue, different methods are suggested. One of the most considered of these methods is using Lost Circulation Materials (LCM). In this thesis, it was tried to manage the situation with Designing and engineering of lost circulation materials for different lost... 

    Passive position finding of stationary targets: Based on circulation and the least square concept

    , Article ISPACS 2012 - IEEE International Symposium on Intelligent Signal Processing and Communications Systems ; 2012 , Pages 390-394 ; 9781467350815 (ISBN) Ahmadian, A ; Mahdavi, A ; Jamshidi, Z ; Sharif University of Technology
    2012
    Abstract
    A method for two dimensional position finding of stationary targets whose bearing measurements suffers from indeterminable bias and random noise has been proposed. The algorithm uses convex optimization to minimize an error function which has been calculated based on circular as well as linear loci of error. Taking into account a number of observations, certain modifications have been applied to the initial crude method so as to arrive at a faster, more accurate method. Simulation results of the method illustrate up to 30% increase in accuracy compared with the well-known least square filter  

    Bias correction of climate modeled temperature and precipitation using artificial neural networks

    , Article Journal of Hydrometeorology ; Volume 18, Issue 7 , 2017 , Pages 1867-1884 ; 1525755X (ISSN) Moghim, S ; Bras, R. L ; Sharif University of Technology
    Abstract
    Climate studies and effective environmental management require unbiased climate datasets. This study develops a new bias correction approach using a three-layer feedforward neural network to reduce the biases of climate variables (temperature and precipitation) over northern South America. Air and skin temperature, specific humidity, and net longwave and shortwave radiation are used as inputs to the network for bias correction of 6-hourly temperature. Inputs to the network for bias correction of monthly precipitation are precipitation at lag 0, 1, 2, and 3 months, and also the standard deviation of precipitation from 3 × 3 neighbors around the pixel of interest. The climate model data are... 

    Effects of Fluctuation in Urmia Lake Water Level on Local Climate of Basin

    , M.Sc. Thesis Sharif University of Technology Dehghanipour, Amir Hossien (Author) ; Tajrishi, Masoud (Supervisor)
    Abstract
    Saline and fresh water lakes comprise a high proportion of the surface water resources and take effects from climate, hydrological, geomorphological changes and human activities in their basins. Variation in area of lakes causes changes in weather and local climate of their basins. Due to high environmental value of lakes and their particular effects on the ecosystem of the region, they have been always center of attention. Lake Urmia as the greatest lake in IRAN and the second largest saline lake in the world always has been considered by many researchers. In recent years Lake Urmia has had many changes such as decrease in area and level. Various factors such as climate change, periodic... 

    CTC Cluster Separation on Microfluidics Chip

    , M.Sc. Thesis Sharif University of Technology Rostami, Peyman (Author) ; Firouzabadi, Bahar (Supervisor) ; Saidi, Mohammad Said (Supervisor)
    Abstract
    According to statistics in 2012, around 14 million people worldwide have cancer, and 8 million have died that year, according to estimates, this number will increase to 21 millions new cancer case and 13 million mortality in 2030. Despite years of research on cancer, many questions about the mechanism of the spread of cancer in the body remain unanswered so far. The proposed models identify that the cells isolated from the primary tumor and transmit them to the circulatory system in the form of circulating tumor cells (CTCs) or in the form of clusters as responsible for the incidence of cancer. This process is called metastasis. Recent studies have reported the high potential of metastasis... 

    A new insight to deformability correlation of circulating tumor cells with metastatic behavior by application of a new deformability-based microfluidic chip

    , Article Analytica Chimica Acta ; Volume 1186 , 2021 ; 00032670 (ISSN) Hakim, M ; Khorasheh, F ; Alemzadeh, I ; Vossoughi, M ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    Isolation and characterization of circulating tumor cells (CTCs) found in blood samples of cancer patients have been considered as a reliable source for cancer prognosis and diagnosis. A new continuous microfluidic platform has been designed in this investigation for simultaneous capture and characterization of CTCs based on their deformability. The deformability-based chip (D-Chip) consists of two sections of separation and characterization where slanted weirs with a gap of 7 μm were considered. Although sometimes CTCs and leukocytes have the same size, the deformability differs in such a way that can be exploited for enrichment purposes. MCF7 and MDA-MB-231 cell lines were used for the... 

    Design and Analysis of Graphene-based Terahertz Nanocircuits

    , M.Sc. Thesis Sharif University of Technology Jafargholi, Ali (Author) ; Borji, Amir (Supervisor)
    Abstract
    In the year 2004 when the first instance of graphen was built in laboratory, entice the attraction of many research groups. Because in spite of absence of graphen to that time, physicists given the unique properties for it. So it was the time to use that marvel properties which only theoretically available, to design and built one atom thick circuits. In this dissertation for the first time, we want by using method of moment and multilayer green functions in spectral domain, analyze graphene-based ribbon and stepped electrical conductivity distribution waveguides and calculate their characteristics such as propagation constant, surface currents and characteristics impedance with external... 

    Design and Fabrication of a Microfluidic Device for Hydrodynamic Label-Free Isolation of Circulating Tumor Cells From Blood

    , M.Sc. Thesis Sharif University of Technology Dorri Giv, Dina (Author) ; Vosoughi, Manouchehr (Supervisor) ; Alemzadeh, Iran (Supervisor)
    Abstract
    Circulating tumor cells (CTCs) are cancer cells which shed from the primary tumor, enter circulation and spread cancer all over the body. CTCs give valuable information about cancer and can help diagnosis and prognosis. Hence separating and isolating CTCs from blood is a necessity for cancer therapeutics. CTCs are separated from blood cells by their different physical or biochemical properties. Many groups have attempted different methods for separation of CTCs. Inertial microfluidics is one of the newest approaches in CTC separation technologies which separates CTCs based on their size. Current inertial microfluidic systems containing straight, spiral, serpentine and contraction expansion... 

    Feasibility Study of Drilling Foam Formulation in Iran

    , M.Sc. Thesis Sharif University of Technology Hadi, Hossein (Author) ; Massihi, Mohsen (Supervisor) ; Shadizadeh, Reza (Supervisor)
    Abstract
    Nowadays, foaming agents have wide applications in drilling, cementing, fracturing and oil displacement in the petroleum industry. Typical applications are to make light fluids for drilling operations in naturally fractured reservoirs where lost circulation is a problem. Compared with conventional and aerated drilling fluids, foamy mud is a compressible and relatively homogeneous mixture. A great flexibility for pressure control is thus possible. In this study, a new foaming agent of Yas-Khorramshahr Company is introduced to drilling fluids. Stability of this agent at different concentration and in presence of Salt and crude oil is tested. Also common drilling muds are lightened and...