Search for: clinical-assessments
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    Designing a fuzzy rule based system to estimate depth of anesthesia

    , Article 1st IEEE Symposium on Computational Intelligence and Data Mining, CIDM 2007, Honolulu, HI, 1 April 2007 through 5 April 2007 ; 2007 , Pages 681-687 ; 1424407052 (ISBN); 9781424407057 (ISBN) Esmaeili, V ; Assareh, A ; Shamsollahi, M. B ; Moradi, M. H ; Arefian, N. M ; Sharif University of Technology
    Estimating the depth of anesthesia (DOA) is still a challenging area in anesthesia research. The objective of this study was to design a fuzzy rule based system which integrates electroencephalogram (EEG) features to quantitatively estimate the DOA. The proposed method is based on the analysis of single-channel EEG using frequency and time domain features as well as Shannon entropy measure. The fuzzy classifier is trained with features obtained from four subsets of data comprising well-defined anesthesia states: awake, moderate, general anesthesia, and isoelectric. The classifier extracts efficient fuzzy if-then rules and the DOA index is derived between 100 (full awake) to 0 (isoelectric)... 

    Prevalence of smoking in 15-64 years old population of North of Iran: Meta-analysis of the results of non-communicable diseases risk factors surveillance system

    , Article Acta Medica Iranica ; Volume 51, Issue 7 , 2013 , Pages 494-500 ; 00446025 (ISSN) Ardeshiri, M. J ; Moosazadeh, M ; Masouleh, M. F ; Kiani, A ; Fakhri, M ; Sharif University of Technology
    Smoking is known as a major cause of chronic obstructive pulmonary disease (COPD) and hence immediate and effective interventions are required for its elimination. This study aimed to collect valid data with regard to cigarette smoking in adult population of north of Iran for policy making by a meta-analysis of the documents of national non-communicable disease risk factors surveillance system. We investigated relevant evidences by searching in published and non-electronic databases. Data were extracted based on variables such as year of the study, sex, age group and prevalence of smoking habit. Based on results of heterogeneity, we applied fixed or random effects model to estimate the... 

    Effects of cognitive load on the amount and temporal structure of postural sway variability in stroke survivors

    , Article Experimental Brain Research ; Volume 236, Issue 1 , 2018 , Pages 285-296 ; 00144819 (ISSN) Mehdizadeh, H ; Khalaf, K ; Ghomashchi, H ; Taghizadeh, G ; Ebrahimi, I ; Taghavi Azar Sharabiani, P ; Mousavi, S. J ; Parnianpour, M ; Sharif University of Technology
    Springer Verlag  2018
    This study aimed to investigate the variability in postural sway patterns during quiet standing in stroke survivors. The postural sway was measured in 19 stroke survivors, as well as 19 healthy demographically matched participants, at 3 levels of postural difficulty (rigid surface with closed and open eyes, and foam surface with closed eyes), and 3 levels of cognitive difficulty (without a cognitive task, easy and difficult cognitive tasks). Both linear analyses (the amount of postural sway variability, including the standard deviation of the COP velocity in both the anteroposterior (AP) and mediolateral (ML) directions), as well as non-linear analyses [the temporal structure of the COP... 

    Disentangling stability and flexibility degrees in Parkinson's disease using a computational postural control model

    , Article Journal of NeuroEngineering and Rehabilitation ; Volume 16, Issue 1 , 2019 ; 17430003 (ISSN) Rahmati, Z ; Schouten, A. C ; Behzadipour, S ; Taghizadeh, G ; Firoozbakhsh, K ; Sharif University of Technology
    BioMed Central Ltd  2019
    Background: Impaired postural control in Parkinson's disease (PD) seriously compromises life quality. Although balance training improves mobility and postural stability, lack of quantitative studies on the neurophysiological mechanisms of balance training in PD impedes the development of patient-specific therapies. We evaluated the effects of a balance-training program using functional balance and mobility tests, posturography, and a postural control model. Methods: Center-of-pressure (COP) data of 40 PD patients before and after a 12-session balance-training program, and 20 healthy control subjects were recorded in four conditions with two tasks on a rigid surface (R-tasks) and two on foam.... 

    How resiliency and hope can predict stress of covid-19 by mediating role of spiritual well-being based on machine learning

    , Article Musculoskeletal Science and Practice ; Volume 51 , 2021 ; 24688630 (ISSN) Noorollahzadeh, K ; Kahrizi, S ; Fesharaki, M. G ; Heidarian, M ; Neblett, R ; Behzadipour, S ; Sharif University of Technology
    Elsevier Ltd  2021
    Background: The Central Sensitization Inventory (CSI) is a patient-reported tool to assess symptoms associated with central sensitization (CS). It consists of two parts: Part A assesses 25 somatic and emotional CS-related health symptoms, and part B asks if one has previously been diagnosed with a list of 10 Central Sensitivity Syndromes and related conditions. Objectives: The aim of this study was to translate and cross-culturally adapt the CSI into Persian and to evaluate its psychometric properties. Design: Cross-sectional study. Method: After completing the Persian translation, the psychometric properties of the Persian CSI (CSI-Per) were evaluated in 256 patients with chronic pain and... 

    Wolfram-like syndrome with bicuspid aortic valve due to a homozygous missense variant in CDK13

    , Article Journal of Human Genetics ; Volume 66, Issue 10 , 2021 , Pages 1009-1018 ; 14345161 (ISSN) Acharya, A ; Raza, S. I ; Zeeshan Anwar, M ; Bharadwaj, T ; Liaqat, K ; Khokhar, M. A. S ; Everard, J. L ; Nasir, A ; Nickerson, D. A ; Bamshad, M. J ; Ansar, M ; Schrauwen, I ; Ahmad, W ; Leal, S. M ; Sharif University of Technology
    Springer Nature  2021
    Background: Wolfram syndrome (WFS) is characterized by deafness, diabetes mellitus, and diabetes insipidus along with optic atrophy. WFS has an autosomal recessive mode of inheritance and is due to variants in WFS1 and CISD2. Methods: We evaluated the underlying molecular etiology of three affected members of a consanguineous family with hearing impairment, bicuspid aortic valve, diabetes mellitus and insipidus, clinodactyly, and gastrointestinal tract abnormalities via exome sequencing approach. We correlated clinical and imaging data with the genetic findings and their associated phenotypes. Results: We identified a homozygous missense variant p.(Asn1097Lys) in CDK13, a gene previously... 

    Objective measurement of inferior-directed stiffness in glenohumeral joint using a specially designed robotic device in healthy shoulders; within- and between-session reliability

    , Article Journal of Biomechanics ; Volume 127 , 2021 ; 00219290 (ISSN) Azarsa, M. H ; Mirbagheri, A. R ; Hosseini, R ; Shadmehr, A ; Karimi, N ; Sharif University of Technology
    Elsevier Ltd  2021
    Clinical assessment of capsuloligamentous structures of the glenohumeral joint has been qualitative and subjective in nature, as demonstrated by limited intra- and inter-rater reliability. Robotic devices were utilized to develop a clinically objective measurement technique for glenohumeral joint stiffness. The purpose of this study was to quantify the amount of inferior-direction stiffness of the glenohumeral joint using a safe clinical device in the asymptomatic individuals, and to determine between trial and between session reliability of the robotic device. Twenty healthy subjects were recruited via convenience sampling. Inferior-directed translation and applying force were measured... 

    Reliability and validity of the Persian version of Foot and Ankle Ability Measure (FAAM) to measure functional limitations in patients with foot and ankle disorders

    , Article Osteoarthritis and Cartilage ; Volume 18, Issue 6 , 2010 , Pages 755-759 ; 10634584 (ISSN) Mazaheri, M ; Salavati, M ; Negahban, H ; Sohani, S. M ; Taghizadeh, F ; Feizi, A ; Karimi, A ; Parnianpour, M ; Sharif University of Technology
    Objective: To translate the Foot and Ankle Ability Measure (FAAM) into Persian and to evaluate the psychometric properties of the Persian version of FAAM. Methods: 93 patients with a range of foot and ankle disorders, completed the Persian version of the FAAM and Short-Form 36 Health Survey (SF-36) in the test session. With an interval of 2-6 days, 60 patients filled out the FAAM in the retest session. The FAAM is composed of two subscales including activities of daily living (ADL) and SPORTS. Internal consistency was assessed using Cronbach's alpha, test-retest reliability using intraclass correlation coefficient (ICC) and standard error of measurement (s.e.m.), item internal consistency... 

    Findings of DTI-p maps in comparison with T 2 /T 2 -FLAIR to assess postoperative hyper-signal abnormal regions in patients with glioblastoma 08 Information and Computing Sciences 0801 Artificial Intelligence and Image Processing

    , Article Cancer Imaging ; Volume 18, Issue 1 , 2018 ; 14707330 (ISSN) Beigi, M ; Safari, M ; Ameri, A ; Shojaee Moghadam, M ; Arbabi, A ; Tabatabaeefar, M ; Salighehrad, H ; Sharif University of Technology
    BioMed Central Ltd  2018
    Purpose: The aim of this study was to compare diffusion tensor imaging (DTI) isotropic map (p-map) with current radiographically (T 2/T 2 -FLAIR) methods based on abnormal hyper-signal size and location of glioblastoma tumor using a semi-automatic approach. Materials and methods: Twenty-five patients with biopsy-proved diagnosis of glioblastoma participated in this study. T 2, T 2 -FLAIR images and diffusion tensor imaging (DTI) were acquired 1 week before radiotherapy. Hyper-signal regions on T 2, T 2 -FLAIR and DTI p-map were segmented by means of semi-automated segmentation. Manual segmentation was used as ground truth. Dice Scores (DS) were calculated for validation of semiautomatic... 

    Postural control learning dynamics in Parkinson's disease: Early improvement with plateau in stability, and continuous progression in flexibility and mobility

    , Article BioMedical Engineering Online ; Volume 19, Issue 1 , 2020 Rahmati, Z ; Behzadipour, S ; Schouten, A. C ; Taghizadeh, G ; Firoozbakhsh, K ; Sharif University of Technology
    BioMed Central Ltd  2020
    Background: Balance training improves postural control in Parkinson's disease (PD). However, a systematic approach for the development of individualized, optimal training programs is still lacking, as the learning dynamics of the postural control in PD, over a training program, are poorly understood. Objectives: We investigated the learning dynamics of the postural control in PD, during a balance-training program, in terms of the clinical, posturographic, and novel model-based measures. Methods: Twenty patients with PD participated in a balance-training program, 3 days a week, for 6 weeks. Clinical tests assessed functional balance and mobility pre-training, mid-training, and post-training.... 

    Revised NIOSH Lifting Equation May generate spine loads exceeding recommended limits

    , Article International Journal of Industrial Ergonomics ; Volume 47 , 2015 , Pages 1-8 ; 01698141 (ISSN) Arjmand, N ; Amini, M ; Shirazi Adl, A ; Plamondon, A ; Parnianpour, M ; Sharif University of Technology
    Elsevier  2015
    The 1991 NIOSH Lifting Equation (NLE) is widely used to assess the risk of injury to spine by providing estimates of the recommended weight limit (RWL) in hands. The present study uses the predictive equations developed based on a detailed trunk musculoskeletal biomechanical model to verify whether the RWL generates L5-S1 loads within the limits (e.g., 3400N for compression recommended by NIOSH and 1000N for shear recommended in some studies). Fifty lifting activities are simulated here to evaluate the RWL by the NLE and the L5-S1 loads by the predictive equations. In lifting activities involving moderate to large forward trunk flexion, the estimated RWL generates L5-S1 spine loads exceeding... 

    MicroRNAs 29, 150, 155, 223 level and their relation to viral and immunological markers in HIV-1 infected naive patients

    , Article Future Virology ; Volume 13, Issue 9 , 2018 , Pages 637-645 ; 17460794 (ISSN) Moghoofei, M ; Bokharaei Salim, F ; Esghaei, M ; Keyvani, H ; Honardoost, M ; Mostafaei, S ; Ghasemi, A ; Tavakoli, A ; Javanmard, D ; Babaei, F ; Garshasbi, S ; Monavari, S. H ; Sharif University of Technology
    Aim: The aim of this study was to assess the relationship between microRNAs and viral and immunological markers in HIV-1 infection. Materials & methods: The expression level of miRNAs was evaluated in 60 HIV-1 patients and 20 healthy controls using real-time PCR assays. Results: The results showed that among all miRNAs, miR-29 and miR-150 were significantly downregulated in HIV-1 patients compared with healthy controls, while miR-155 and miR-223 were significantly upregulated compared with healthy controls (p < 0.001 for all comparisons). Conclusion: The mentioned miRNAs seem to influence the clinical progression of HIV-1 infection in naive patients. Moreover, determining the profiles of... 

    The metabolome profiling of obese and non-obese individuals: Metabolically healthy obese and unhealthy non-obese paradox

    , Article Iranian Journal of Basic Medical Sciences ; Volume 23, Issue 2 , 2020 , Pages 186-194 Chashmniam, S ; Madani, N. H ; Ghoochani, B. F. N. M ; Safari Alighiarloo, N ; Khamseh, M. E ; Sharif University of Technology
    Mashhad University of Medical Sciences  2020
    Objective(s): The molecular basis of “metabolically healthy obese” and “metabolically unhealthy non-obese” phenotypes is not fully understood. Our objective was to identify metabolite patterns differing in obese (metabolically healthy vs unhealthy (MHO vs MUHO)) and non-obese (metabolically healthy vs unhealthy (MHNO vs MUHNO)) individuals. Materials and Methods: This case-control study was performed on 86 subjects stratified into four groups using anthropometric and clinical measurements: MHO (21), MUHO (21), MHNO (22), and MUHNO (22). Serum metabolites were profiled using nuclear magnetic resonance (NMR). Multivariate analysis was applied to uncover discriminant metabolites, and enrichment...