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clinical-decision-making
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A clinical decision support system based on support vector machine and binary particle swarm optimisation for cardiovascular disease diagnosis
, Article International Journal of Data Mining and Bioinformatics ; Volume 15, Issue 4 , 2016 , Pages 312-327 ; 17485673 (ISSN) ; Shavandi, H ; Sadeghi, M ; Sharif University of Technology
Inderscience Enterprises Ltd
2016
Abstract
Cardiovascular diseases have been known as one of the main reasons of mortality all around the world. Nevertheless, this disease is preventable if it can be diagnosed in an early stage. Therefore, it is crucial to develop Clinical Decision Support Systems (CDSSs) that are able to help physicians diagnose the disease and its related risks. This study focuses on cardiovascular disease diagnosis in an Iranian community by developing a CDSS, based on Support Vector Machine (SVM) combined with Binary Particle Swarm Optimisation (BPSO). We used SVM as the classifier and benefited enormously from optimisation capabilities of BPSO in model development as well as feature selection. Finally,...
An expert system for selecting wart treatment method
, Article Computers in Biology and Medicine ; Volume 81 , 2017 , Pages 167-175 ; 00104825 (ISSN) ; Alizadehsani, R ; Roshanzamir, M ; Khosravi, A ; Layegh, P ; Nahavandi, S ; Sharif University of Technology
Elsevier Ltd
2017
Abstract
As benign tumors, warts are made through the mediation of Human Papillomavirus (HPV) and may grow on all parts of body, especially hands and feet. There are several treatment methods for this illness. However, none of them can heal all patients. Consequently, physicians are looking for more effective and customized treatments for each patient. They are endeavoring to discover which treatments have better impacts on a particular patient. The aim of this study is to identify the appropriate treatment for two common types of warts (plantar and common) and to predict the responses of two of the best methods (immunotherapy and cryotherapy) to the treatment. As an original work, the study was...
A fuzzy expert system for prescribing atorvastatin optimum dose
, Article Koomesh ; Volume 13, Issue 1 , 2011 , Pages 43-50 ; 16087046 (ISSN) ; Hassanpour Ezatti, M ; Navidi, H ; Abachi, T ; Sharif University of Technology
2011
Abstract
Introduction: Today, Fuzzy expert systems have helped physicians in cases of uncertainty in medical decision making for prescribing drugs. Narrowing of coronary heart and reduction in heart blood flow are important causes of coronary heart disease (CHD). Control of blood lipid level is a routine treatment in CHD patients. But damage to liver is a common side effect of lipid lowering drug medication. Measurement of plasma Alanine aminotransferase level is considered as a marker of liver damage. The aim of this study was to determination of optimal dose of atorvastatin using Fuzzy expert system. Materials and Methods: in this study, Fuzzy expert system based on drug dose determination was...
Using a motion sensor to categorize nonspecific low back pain patients: A machine learning approach
, Article Sensors (Switzerland) ; Volume 20, Issue 12 , 2020 , Pages 1-16 ; Ashouri, S ; Abedi, M ; Azadeh Fard, N ; Parnianpour, M ; Khalaf, K ; Rashedi, E ; Sharif University of Technology
MDPI AG
2020
Abstract
Nonspecific low back pain (NSLBP) constitutes a critical health challenge that impacts millions of people worldwide with devastating health and socioeconomic consequences. In today’s clinical settings, practitioners continue to follow conventional guidelines to categorize NSLBP patients based on subjective approaches, such as the STarT Back Screening Tool (SBST). This study aimed to develop a sensor-based machine learning model to classify NSLBP patients into different subgroups according to quantitative kinematic data, i.e., trunk motion and balance-related measures, in conjunction with STarT output. Specifically, inertial measurement units (IMU) were attached to the trunks of ninety-four...
Biomechanical analysis of the pelvis angular excursion in sagittal plane in response to asymmetric leg loading tasks in females with and without nonspecific chronic low back pain
, Article Journal of Biomedical Physics and Engineering ; Volume 11, Issue 3 , 2021 , Pages 367-376 ; 22517200 (ISSN) ; Kamali, F ; Parni Anpour, M ; Davoudi, M ; Sharif University of Technology
Shriaz University of Medical Sciences
2021
Abstract
Background: Controlling pelvic excursions is the focus of stabilization exercises such as legs loading tasks in rehabilitation of non-specific chronic low back pain (NSCLBP) patients. Progression of these exercises is based on the ability to perform tasks with minimal sagittal pelvic excursions. In spite of emphasis on minimizing pelvic motions, no previous studies have investigated kinematic analysis of the pelvic excursions during leg loading exercises in NSCLBP patients. Objective: This study aims to investigate the sagittal pelvis excursion during performing asymmetric leg loading tasks in individuals with and without NSCLBP. Material and Methods: In this cross-sectional study, kinematic...
Telemedicine and computer-based technologies during coronavirus disease 2019 infection; a chance to educate and diagnose
, Article Archives of Iranian Medicine ; Volume 23, Issue 8 , 2020 , Pages 561-563 ; Mirzaei Fard, M ; Habibi Hatam Ghale, F ; Rezaei Kalat, A ; Fathi, A ; Shariati, M ; Sadr Nabavi, A ; Miri, R ; Bidkhori, H. R ; Aelami, M. H ; Sharif University of Technology
Academy of Medical Sciences of I.R. Iran
2020
Abstract
Coronavirus disease 2019 (COVID-19) is now of global concern due to its rapid dissemination across the globe. The rapid spread of this viral infection, along with many of its unknown aspects, has posed new challenges to the health care systems. The main challenging effects of COVID-19 are rapid dissemination through close contact and varying clinical severity among different individuals. Furthermore, the medical staff in endemic areas are becoming exhausted and deal with a considerable level of job burnout, which can negatively affect their medical decision making. Also, due to the variable pulmonary manifestations of COVID-19, some physicians may misdiagnose patients. To overcome these...
Lower extremity kinematic analysis in male athletes with unilateral anterior cruciate reconstruction in a jump-landing task and its association with return to sport criteria
, Article BMC Musculoskeletal Disorders ; Volume 20, Issue 1 , 2019 ; 14712474 (ISSN) ; Esfandiarpour, F ; Mehdizadeh, S ; Yousefzadeh, N. K ; Parnianpour, M ; Sharif University of Technology
BioMed Central Ltd
2019
Abstract
Background: Return to sport (RTS) criteria are widely being used to identify anterior cruciate ligament reconstructed (ACLR) athletes ready to return to sportive activity and reduce risk of ACL re-injury. However, studies show a high rate of ACL re-injury in athletes who passed RTS criteria. This indicates that the current RTS criteria might not be sufficient to determine return to sport time in ACLR athletes. Previous studies have reported a close association between altered lower limb kinematics and ACL re-injury. However, it is not clear how lower extremity kinematics differs between ACLR athletes who passed the RTS-criteria and who failed. This study compared lower extremity kinematics...
The biomechanical response of the lower cervical spine post laminectomy: geometrically-parametric patient-specific finite element analyses
, Article Journal of Medical and Biological Engineering ; Volume 41, Issue 1 , 2021 , Pages 59-70 ; 16090985 (ISSN) ; Cheng, C. H ; Wang, J. L ; Niu, C. C ; Parnianpour, M ; Khalaf, K ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
Purpose: This study aimed to investigate the biomechanical impact of laminectomy on cervical intersegmental motion and load sharing using a parametric patient-specific finite element (FE) model towards providing clinicians with a viable quantitative tool for informed decision-making and improved surgical planning. Methods: Ten subject-specific nonlinear osteo-ligamentous cervical spine (C3–C7) FE models were developed using X-ray image-based algorithms. The models were used to evaluate the effect of laminectomy on lower cervical spine biomechanics for two-level (C3–C4) and three-level (C3–C5) laminectomy procedures. Results: The average cervical spine ranges of motion (ROM) for the pre-op...