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    Design and Manufacture of a Scaffold with a Drug Delivery System for a Better Tissue Wound Healing Process

    , M.Sc. Thesis Sharif University of Technology Shaygani, Hossein (Author) ; Shamloo, Amir (Supervisor) ; Aryanpour, Masoud (Supervisor)
    Abstract
    Articular cartilage is devoid of blood vessels, lymphatics, and nerves which gives it a very limited intrinsic healing and repair capabilities. Being under constant harsh biomechanical environment, makes maintaining the health of articular cartilage a vital principle in having healthy joints. Tissue engineering as a method for regeneration of damaged tissue have attracted a lot of attention. Articular cartilage engineered scaffolds act as a macro scale drug delivery system which in addition to having a good mechanical properties similar to that of cartilage tissue, have to provide a highly porous environment for cell migration and proliferation. The aim of this study is to fabricate a drug...