Sharif Digital Repository

Background: Planarians are non-parasitic Platyhelminthes (flatworms) famous for their regeneration ability and for having a well-organized brain. Dugesia japonica is a typical planarian species that is widely distributed in the East Asia. Extensive cellular and molecular experimental methods have been developed to identify the functions of thousands of genes in this species, making this planarian a good experimental model for regeneration biology and neurobiology. However, no genome-level information is available for D. japonica, and few gene regulatory networks have been identified thus far. Results: To obtain whole-genome information on this species and to study its gene regulatory... 

In this paper, flow of multi-component two-phase fluids in highly heterogeneous anisotropic two-dimensional porous media is studied using computational methods suitable for unstructured triangular and/or quadrilateral grids. The physical model accounts for miscibility and compressibility of fluids while gravity and capillary effects are neglected. The governing equations consist of a pressure equation together with a system of mass conservation equations. For solving pressure equation, a new method called Control Volume Distributed Finite Element Method (CVDFEM) is introduced which uses Control Volume Distributed (CVD) vertex-centered grids. It is shown that the proposed method is able to... 

Purpose: This paper aims to numerically study the compositional flow of two- and three-phase fluids in one-dimensional porous media and to make a comparison between several upwind and central numerical schemes. Design/methodology/approach: Implicit pressure explicit composition (IMPEC) procedure is used for discretization of governing equations. The pressure equation is solved implicitly, whereas the mass conservation equations are solved explicitly using different upwind (UPW) and central (CEN) numerical schemes. These include classical upwind (UPW-CLS), flux-based decomposition upwind (UPW-FLX), variable-based decomposition upwind (UPW-VAR), Roe’s upwind (UPW-ROE), local Lax–Friedrichs... 

Load management and cost optimization are among the important factors in trigeneration systems and combined cooling, heating and power (CCHP) systems. In this study, an innovative CCHP system uses a gas turbine as the prime mover and has a heat recovery steam generator (HRSG) in addition to an auxiliary boiler, electric and absorption chillers. The system is tied with the bulk electric grid; to export and sell excess power or import power when necessary. This study analyzes load management and cost optimization of CCHP systems. A heuristic strategy to optimize the total energy cost is then presented. The optimal size of CCHP is determined from the study results. This paper proposes a model... 

The ideas of creatio ex nihilo of the universe and creatio continua of new matter out of nothing entered the arena of natural science with the advent of the Big Bang and the steady-state theories in the mid-twentieth century. Adolf Grünbaum has tried to interpret the steady-state theory in such a way, to show that the continuous formation of new matter out of nothing in this theory can be explained purely physically. In this paper, however, it will be shown that Grünbaum's interpretation encounters at least three problems: not distinguishing between material and efficient causes, inconsistency, and misconceiving the law of density conservation  

A precise thermal-hydraulics model is of great importance for developing more effective designs of High Temperature Gas Cooled Reactors (HTGR). Recently, several advancements have been made in the methods of analysis of porous media which could be of significant value in the development of more precise and robust codes. The objective of this research is to incorporate some of the most recent improvements in the development of a new 2D program for thermal-hydraulics analysis of modular high temperature reactors. The program is mainly based on the solution of a coupled set of mass, energy and momentum conservation equations for the gas flow, along with the energy conservation equation in the... 

This paper presents the mathematical modeling of single-phase natural circulation of the University of Genoa's rectangular loop (LOOP#1) by a computer program and using RELAP5 system code. The mass, momentum and energy conservation equations in transient form were solved numerically using the finite difference method. One-dimensional linear stability analysis was performed for the single-phase natural circulation loop and the numerical perturbation technique was used in this analysis. The Nyquist criterion was employed to find the stability map of the LOOP#1. The obtained transient results using the first order upwind scheme of the fluid temperatures in various sectors of the LOOP#1 are... 

In this article, solving the population balance equation (PBE) and controlling the final particle size for crystallization problems have been addressed. For solving the general form of multidimensional PBE, a numerical method called conservation element and solution element (CE/SE) has been used. By applying this method to one- and two-dimensional crystallization problems, it has been shown that this technique can handle all types of source terms in the PBE. Model accuracy has been checked with experimental data reported in the literature and also with the analytical solution of PB-type equations. Control of final particle size was formulated in an optimization framework. To obtain a desired... 

Purpose - In this paper, the flow of multiphase fluids in a one-dimensional homogeneous porous media involving the gravity effects is numerically studied using the dominant wave method. The paper aims to discuss these issues. Design/methodology/approach - The numerical scheme used for solving the pressure equations, obtained for the black-oil model, is a backward Euler scheme while the hyperbolic mass conservation equations, derived for both black-oil and Buckley-Leverett models, are solved using the dominant wave method. Higher-order schemes are achieved using either variable derivatives along with the minmod limiter or a MUSCL type interface construction scheme using the Fromm's limiter.... 

In a series of essays, beginning with this article, we are going to develop a new formulation of microphenomena based on the principles of reality and causality. The new theory provides us with a new depiction of microphenomena assuming a unified concept of information, matter and energy. So, we suppose that in a definite microphysical context (including other interacting particles), each particle is enfolded by a probability field whose existence is contingent on the existence of the particle, but it can locally affect the physical status of the particle in a context-dependent manner. The dynamics of the whole particle-field system obeys deterministic equations in a manner such that when... 

This study investigates critical run-off and sediment production sources in a forested Kasilian watershed located in northern Iran. The Water Erosion Prediction Project (WEPP) watershed model was set up to simulate the run-off and sediment yields. WEPP was calibrated and validated against measured rainfall-run-off-sediment data. Results showed that simulated run-off and sediment yields of the watershed were in agreement with the measured data for the calibration and validation periods. While low and medium values of run-off and sediment yields were adequately simulated by the WEPP model, high run-off and sediment yield values were underestimated. Performance of the model was evaluated as... 

Despite advancements in developing physics-based formulations to estimate the sheet-flow travel time (tSHF), the quantification of the relative impacts of influential parameters on tSHF has not previously been considered. In this study, a brief review of the physics-based formulations to estimate tSHF including kinematic wave (K-W) theory in combination with Manning's roughness (K-M) and with Darcy-Weisbach friction formula (K-D) over single and multiple planes is provided. Then, the relative significance of input parameters to the developed approaches is quantified by a density-based global sensitivity analysis (GSA). The performance of K-M considering zero-upstream and uniform flow depth... 

Implementation of green management in sport complexes can ensure the continuous arrangement and assessment of activities from the environmental perspective and will end up in control and prevention of contaminants. Enghelab sport complex (ESC) in Iran is selected for this study due to its size and long-term activities. Due to the comprehensive plan of the aforesaid sports complex, numerous centers and departments were established in this site in order to materialize its envisioned sports, recreational and cultural objectives. The results of the questionnaires distributed amongst the members and the personnel of the complex revealed that approximately 50 % occupants were not acquainted with... 

In this paper, collision of two balls in three dimensions with regard to energy loss and friction is studied. This investigation intends to propose the procedure which can determine the condition of pure sliding, sliding with rolling or sticking, and rolling or sticking at the beginning of contact. Furthermore, the other aim of this research is to suggest the closed-form relation for post-collision angular and linear velocities in which the possibility of three regimes of impact, pure sliding, sliding with rolling, and pure rolling, are considered. In this investigation, viscous Hertz contact force describes the normal interaction force. Moreover, stick regime is not taken into account and... 

In this paper, the internal ballistics of solid propellant rocket motor with an arbitrary grain configuration is numerically investigated using quasi one dimensional simulation of Inviscid conservation equations. The upwind Roe's scheme is used to calculate the convective fluxes. Appropriate burning rate model to predict the erosive burning in solid propellant is used here. By using this phenomenon and accurate simulation, tactical motor performance can be considerably improved