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covalent-functionalizations
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Ugi four-component assembly process: An efficient approach for one-pot multifunctionalization of nanographene oxide in water and its application in lipase immobilization
, Article Chemistry of Materials ; Volume 28, Issue 9 , 2016 , Pages 3004-3016 ; 08974756 (ISSN) ; Akhavan, O ; Hashemi, E ; Shamsara, M ; Sharif University of Technology
American Chemical Society
2016
Abstract
Graphene-based materials are revealing the leading edge of advanced technology for their exceptional physical and chemical properties. Chemical manipulation on graphene surface to tailor its unique properties and modify atomic structures is being actively pursued. Therefore, the discovery of robust and general protocols to anchor active functionality on graphene basal plane is still of great interest. Multicomponent reactions promise an enormous level of interest due to addressing both diversity and complexity in combinatorial synthesis, in which more than two starting compounds react to form a product derived from entire inputs. In this article, we present the first covalent...
Hyperthermia response of PEGylated magnetic graphene nanocomposites for heating applications and accelerate antibacterial activity using magnetic fluid hyperthermia
, Article Applied Physics A: Materials Science and Processing ; Volume 126, Issue 4 , 2020 ; Shih, P. J ; Soufi Zomorod, M ; Heravi, P ; Ahadian, M. M ; Hatami, N ; Sharif University of Technology
Springer
2020
Abstract
In this research work, graphene/cobalt nanocomposites are functionalized with polyethylene glycol (PEG) to be a platform for theranostics application and antibacterial activity. The non-covalent functionalization of PEG on the surfaces of nanocomposites improved their stability and diminished their cytotoxicity. The PEGylated nanocomposites are demonstrated to allow simultaneous administration of two cancer therapy methods such as magnetic fluids hyperthermia (MFH) which is carried out by converting magnetic energy into heat through ferromagnetic cobalt nanoparticles and heat generation through near-infrared optical absorption by the reduced graphene oxide. A concise simulation is carried...