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cytocompatibility
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Magnetic nanocomposites for biomedical applications
, Article Advances in Colloid and Interface Science ; Volume 308 , 2022 ; 00018686 (ISSN) ; Ghovvati, M ; Rabiee, N ; Ahmadi, S ; Abbariki, N ; Sojdeh, S ; Ojaghi, A ; Bagherzadeh, M ; Akhavan, O ; Sharifi, E ; Rabiee, M ; Saeb, M. R ; Bolouri, K ; Webster, T. J ; Zare, E. N ; Zarrabi, A ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Tissue engineering and regenerative medicine have solved numerous problems related to the repair and regeneration of damaged organs and tissues arising from aging, illnesses, and injuries. Nanotechnology has further aided tissue regeneration science and has provided outstanding opportunities to help disease diagnosis as well as treat damaged tissues. Based on the most recent findings, magnetic nanostructures (MNSs), in particular, have emerged as promising materials for detecting, directing, and supporting tissue regeneration. There have been many reports concerning the role of these nano-building blocks in the regeneration of both soft and hard tissues, but the subject has not been...
Pyrolytic carbon coating for cytocompatibility of titanium oxide nanoparticles: A promising candidate for medical applications
, Article Nanotechnology ; Volume 23, Issue 4 , 2012 ; 09574484 (ISSN) ; Imani, M ; Yousefi, M ; Galinetto, P ; Simchi, A ; Amiri, H ; Stroeve, P ; Mahmoudi, M ; Sharif University of Technology
2012
Abstract
Nanoparticles for biomedical use must be cytocompatible with the biological environment that they are exposed to. Current research has focused on the surface functionalization of nanoparticles by using proteins, polymers, thiols and other organic compounds. Here we show that inorganic nanoparticles such as titanium oxide can be coated by pyrolytic carbon (PyC) and that the coating has cytocompatible properties. Pyrolization and condensation of methane formed a thin layer of pyrolytic carbon on the titanium oxide core. The formation of the PyC shell retards coalescence and sintering of the ceramic phase. Our MTT assay shows that the PyC-coated particles are cytocompatible at employed doses
Stereolithography 3D bioprinting method for fabrication of human corneal stroma equivalent
, Article Annals of Biomedical Engineering ; Volume 48, Issue 7 , June , 2020 , Pages 1955-1970 ; Abdekhodaie, M. J ; Kumar, H ; Mashayekhan, S ; Baradaran Rafii, A ; Kim, K ; Sharif University of Technology
Springer
2020
Abstract
Abstract: 3D bioprinting technology is a promising approach for corneal stromal tissue regeneration. In this study, gelatin methacrylate (GelMA) mixed with corneal stromal cells was used as a bioink. The visible light-based stereolithography (SLA) 3D bioprinting method was utilized to print the anatomically similar dome-shaped structure of the human corneal stroma. Two different concentrations of GelMA macromer (7.5 and 12.5%) were tested for corneal stroma bioprinting. Due to high macromer concentrations, 12.5% GelMA was stiffer than 7.5% GelMA, which made it easier to handle. In terms of water content and optical transmittance of the bioprinted scaffolds, we observed that scaffold with...