Sharif Digital Repository

Cooling water is used to remove the heat from stator bar of large turbogenerators and prevent additional temperature rise. Blockage of these channels leads to heat traps along the stator bar and its temperature failure. In addition, transposition of strands in a bar causes accumulation of heat in some parts of stator bar because of non-uniform arrangement of cooling channels especially when some of channels are blocked. In this paper, effect of cooling water channels blockage is studied using a precise thermal model. It is shown that such heat traps cause additional temperature rise in stator bars and this phenomenon can not be detected by thermal sensors of turbogenerator. Laboratory and... 

Normal human breathing exhibits complex variability in both respiratory rhythm and volume. Analyzing such nonlinear fluctuations may provide clinically relevant information in patients with complex illnesses such as asthma. We compared the cycle-by-cycle fluctuations of inter-breath interval (IBI) and lung volume (LV) among healthy volunteers and patients with various types of asthma. Continuous respiratory datasets were collected from forty agematched men including 10 healthy volunteers, 10 patients with controlled atopic asthma, 10 patients with uncontrolled atopic asthma, and 10 patients with uncontrolled non-atopic asthma during 60 min spontaneous breathing. Complexity of breathing... 

Compressor fault identification is an important part of gas turbine diagnostic systems. Model based techniques have been used widely in this field. In this paper the performance of two compressors has been simulated using stage stacking method. One of them is the NASA 10 stage constant tip diameter compressor. The other one is the Siemens V94.2 engine's compressor. Then a new and more real compressor fault model is introduced and the effect of different faults on compressor performance has been studied. In this paper an intelligent fault diagnostic system has been developed which is able to detect different faults of the compressor. In all of the cases of faults, degradation in inlet flow... 

Fault tolerant operation of single-ended non-isolated DC-DC converters used in embedded and safety critical applications is mandatory to guaranty service continuity. This paper proposes a new, fast and efficient FPGA-based open and short-circuit switch fault diagnosis asssociated to fault tolerant converter topology. The results of Hardware-In-the-Loop and experimental tests are presented and discussed  

Central heating system faults affect building energy consumption and indoor thermal comfort significantly. The interdependencies among system components and multiple failure modes present a challenge for system health diagnostics and prognostics. A reliable diagnosis and prognosis can only be ensured when all component conditions are monitored with minimum uncertainty. In this regard, sensors should be selected based on their priority in providing system health information. Currently, most of the research on sensor optimization models optimize sensors position and orientation. However, in this study sensor type is optimized as well. In addition, the proposed method is based on the Bayesian... 

This paper presents a mathematical model describing how the physicians actually make a diagnostic decision. Next to a description of diagnostic decision making as done by the physicians, this paper shows that how can we design and develop a new approach to medical diagnosis based on the human principles of decision making. The model was challenged to diagnose a series of actual patients. Real clinical data was entered into the model and the system produced a ranked list of possible diagnoses for each case. The results indicated good performance when compared with internist's diagnosis. The proposed method is effective and can be applied to describe medical reasoning as done by the... 

Capsule endoscopy is a minimally invasive diagnostic technology for gastrointestinal diseases providing images from the human's digestion system. Developing a robust and real-time localization algorithm to determine the orientation and position of the endoscopic capsule is a crucial step toward medical diagnostics. In this paper, we propose a novel model-aided real-time localization approach to estimate the position and orientation of a magnetic endoscopic capsule swimming inside the stomach. In the proposed method, the governing equations of the motion of an ellipsoidal capsule inside the fluid, considering different hydrodynamics interactions, are derived. Then, based on the dynamic model,... 

Since plasma is rich in many biomarkers used in clinical diagnostic experiments, microscale blood plasma separation is a primitive step in most of microfluidic analytical chips. In this paper, a passive microfluidic device for on-chip blood plasma separation based on Zweifach–Fung effect and plasma skimming was designed and fabricated by hot embossing of microchannels on a PMMA substrate and thermal bonding process. Human blood was diluted in various times and injected into the device. The main novelty of the proposed microfluidic device is the design of diffuser-shaped daughter channels. Our results demonstrated that this design exerted a considerable positive influence on the separation... 

In this study, we are proposing a novel nonlinear classification approach to discriminate between Alzheimer's Disease (AD) and a control group using T1-weighted and T2-weighted Magnetic Resonance Images (MRI's) of brain. Since T1-weighted images and T2-weighted images have inherent physical differences, obviously each of them has its own particular medical data and hence, we extracted some specific features from each. Then the variations of the relevant eigenvalues of the extracted features were tracked to pick up the most informative ones. The final features were assigned to two parallel systems to be nonlinearly categorized. Considering the fact that AD defects the white and gray regions... 

Since plasma is rich in many biomarkers used in clinical diagnostic experiments, microscale blood plasma separation is a primitive step in most of microfluidic analytical chips. In this paper, a passive microfluidic device for on-chip blood plasma separation based on Zweifach–Fung effect and plasma skimming was designed and fabricated by hot embossing of microchannels on a PMMA substrate and thermal bonding process. Human blood was diluted in various times and injected into the device. The main novelty of the proposed microfluidic device is the design of diffuser-shaped daughter channels. Our results demonstrated that this design exerted a considerable positive influence on the separation... 

The fabrication of ITO-capped WO3 nanowires associated with their bio-sensing properties in field-effect transistor diagnostics basis as a biosensor has been reported. The bio-sensing property for manipulated nanowires elucidated that the grown nanostructures were very sensitive to protein. The ITO-capped WO3 nanowires biosensor showed an intensive bio-sensing activity against reliable protein. Polylysine strongly charged bio-molecule was applied as model system to demonstrate the implementation of materialized biosensor. The employed sensing mechanism was ‘label-free’ and depended on bio-molecule’s intrinsic charge. For nanowires synthesis, the vapor–liquid–solid mechanism was used.... 

The emergence of textile-based wearable sensors as light-weight portable devices to monitor desired parameters, has recently gained much interest and has led to the development of flexible electronics on non-rigid substrates. The flexible biosensors may result in improved sports performance, to monitor the desired bodies for injuries, improved clinical diagnostics and monitor biological molecules and ions in biological fluids such as saliva, sweat. In addition, they could help users with different types of disorders such as blindness. In this context, new composite and nanomaterials have been found to be promising candidates to obtain improved performance of the textile based wearable... 

Segmentation of the human airway tree from volumetric computed tomography images is an important stage for many clinical applications such as virtual bronchoscopy. The main challenges of previously developed methods are to deal with two problems namely, leaking into the surrounding lung parenchyma during segmentation and the need to manually adjust the parameters. To overcome these problems, a multi-seeded fuzzy based region growing approach in conjuction with the spatial information of voxels is proposed. Comparison with a commonly used region growing segmentation algorithm shows that the proposed method retrieves more accurate results by achieving the specificity and sensitivity of 98.81%... 

Laser Powder Deposition (LPD) process is an advanced material processing technique which has many applications. Despite this fact, reliable and accurate control schemes have not yet fully developed for the process. In this paper, the problem of controlling the clad height in the LPD process is studied. Due to a faster response of the process to change in scanning velocity over the laser power, the scanning velocity is selected as the input control variable. Since the governing equations of the LPD process are complex for designing a controller, an identified nonlinear dynamic model is used. The model is a Hammerstein model with a linear dynamic and a nonlinear memoryless block. The model... 

In an attempt to explore the significance of transport theory in neutron noise, localization of a noise source by Green's function based on transport theory is investigated. There are considerable differences between Green's functions based on diffusion and transport, such as small dimensions, near edges, high heterogeneity medium and high-frequency source of perturbation. These differences are expected to significantly impact unfolding, reconstruction, and identification of the neutron noise source. Improvement in noise source unfolding methods is essential in terms of safety aspects and reactor performance enhancement. Since gaining the ability to monitor nuclear reactor based on noise... 

Every year many people suffer from knee injuries. Previous studies on patients with knee injuries have shown that about 40% of knee injuries are Ligament injuries, and about 50% of the ligament injuries are the Anterior Cruciate Ligament (ACL) injuries. Along with other methods, knee arthrometers are widely used to diagnose ACL injuries. In the current research, a knee arthrometer was designed and developed to provide a reliable and repeatable measurement of knee laxity under anteriorposterior applied loads. Testretest configurations to examine repeatability of the device resulted in less than 1.5-mm difference for more than 97% of tests under applied loads of up to 90 N. These tests... 

Carbon-based quantum dots (CQDs) are a newly developed class of carbon nano-materials that have attracted much interest and attention as promising competitors to already available semiconductor quantum dots owing to their un-comparable and unique properties. In addition, controllability of CQDs unique physiochemical properties is as a result of their surface passivation and functionalization. This is an update article (between 2013 and 2016) on the recent progress, characteristics and synthesis methods of CQDs and different advantages in varieties of applications. © 2017 Elsevier Masson SAS  

The current gold standard for clinical diagnosis of melanoma is excisional biopsy and histopathologic analysis. Approximately 15–30 benign lesions are biopsied to diagnose each melanoma. In addition, biopsies are invasive and result in pain, anxiety, scarring, and disfigurement of patients, which can add additional burden to the health care system. Among several imaging techniques developed to enhance melanoma diagnosis, optical coherence tomography (OCT), with its high-resolution and intermediate penetration depth, can potentially provide required diagnostic information noninvasively. Here, we present an image analysis algorithm, "optical properties extraction (OPE)," which improves the...