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    Pyrolytic graphite electrode modified with a thin film of a graphite/diamond nano-mixture for highly sensitive voltammetric determination of tryptophan and 5-hydroxytryptophan

    , Article Microchimica Acta ; Volume 174, Issue 3 , 2011 , Pages 361-366 ; 00263672 (ISSN) Shahrokhian, S ; Bayat, M ; Sharif University of Technology
    2011
    Abstract
    We have prepared a pyrolytic graphite electrode (PGE) whose surface is covered with a thin film of a nano-mixture of graphite/diamond (NGD). The electrode is shown to be capable of electrochemically sensing of tryptophan (TRP) and 5-hydroxytryptophan (HTRP). The presence of the NGD film resulted in a remarkable increase in the peak currents and sharpness of the waves so that submicromolar concentrations of TRP and HTRP become detectable. Potential scan rates, the pH of the solution, the accumulation conditions and the amount of the modifier were optimized via cyclic voltammetry. Linear sweep voltammetry, under optimized accumulation time and in open circuit operation, was applied to the... 

    In-situ preparation and characterization of ultra-high molecular weight polyethylene/diamond nanocomposites using bi-supported Ziegler-Natta catalyst: effect of nanodiamond silanization

    , Article Materials Today Communications ; Volume 14 , March , 2018 , Pages 53-64 ; 23524928 (ISSN) Haddadi, S. A ; Ramezani Saadatabadi, Ahmad ; Amini, M ; Kheradmand, A ; Shsrif University of Technology
    Elsevier Ltd  2018
    Abstract
    In this study, reinforcement of ultra-high molecular weight polyethylene (UHMWPE) was investigated using the sol-gel surface modified diamond nanoparticles (NDs). Nanocomposite samples were synthesized via in-situ polymerization using bi-supported Ziegler-Natta catalyst. Fourier transform infrared spectroscopy, thermogravimetric analysis and contact angle measurements proved the proper silanization (∼1.9%) of NDs. Characterization of the catalysts revealed decrease in the activity of catalysts in presence of NDs which were responsible for the lower average molecular weight of the samples. Field emission scanning electron microscopy revealed an improved dispersion of the modified NDs in... 

    Synthesis and Characterization of Nanodiamond/Epoxy Nanocomposites

    , M.Sc. Thesis Sharif University of Technology Aris, Atousa (Author) ; Shojaei, Akbar (Supervisor) ; Bagheri, Reza (Co-Advisor)
    Abstract
    In recent years, it has been interesting to to use nanodiamond (ND) in oreder to improve mechanical and electrical properties. Producing it in very low dimensions, make it more important to treat ND surface proportional to its application. Hence, with knowledge of influence of ND and its functional groups on curing process, in present research,carboxylic acid and amine were settled on its surface and in addition to untreated ND, they were dispersed in DGEBA epoxy as a reinforcement. Afterward, by adding triethylenetetramine kinetic cure of nanocomposites were investigated. For this purpose, conversion was determined using heat flow of reaction and then activation energy was calculated.... 

    Electrophoretic Deposition of Alginate-Bioglass-Nanodiamond Nanocomposites and Evolution of their Bioactivity

    , M.Sc. Thesis Sharif University of Technology Mansoorianfar, Mojtaba (Author) ; Simchi, Abdollreza (Supervisor)
    Abstract
    Recently, diamond nanoparticles have attracted interest for biomedical applications such as drug delivery, targeted cancer therapies, fabrication of tissue scaffolds and biosensors. In the present work, elecrophoretic deposition (EPD) of nanodiamond-bioactive glass-alginate nanocomposite was studied. In vitro bioactivity and biocompatibility of the nanocomposite were evaluated in simulated body fluid (SBF) and by MTT assay. The EPD process was performed under different conditions in order to obtain a uniform coating on the surface of 316L stainless steel substrate. The stability of the suspension was determined via optical sedimentation method and zeta potential analysis. It was found that... 

    Design and fabrication of a two-phase diamond nanoparticle aided fast PCR device

    , Article Analytica Chimica Acta ; Volume 1068 , 2019 , Pages 28-40 ; 00032670 (ISSN) Madadelahi, M ; Ghazimirsaeed, E ; Shamloo, A ; Sharif University of Technology
    Elsevier B.V  2019
    Abstract
    Polymerase Chain Reaction (PCR) is an important and prevalent technique in biotechnology because of its crucial role in cloning DNA fragments and diagnostic applications. In the present study, a high-throughput two-phase PCR device is designed and fabricated which utilizes a serpentine microchannel together with a spiral structure. The former is for the droplet-generation and mixing and the latter is for the thermal cycling process. Moreover, the effect of diamond nanoparticles (diamondNP) on the performance of PCR is also investigated while using commercial PCR devices and the fabricated PCR device designed in this study. Using numerical simulation, it is shown that within the simple and... 

    Fabrication and Chracatization of Novel Electrospun Chitosan Fibers Reinforced with Bacterial Cellulose and Nanodiamond for Wound Dressing Applications

    , M.Sc. Thesis Sharif University of Technology Ostadhossein, Fatemeh (Author) ; Simchi, Abdolreza (Supervisor)
    Abstract
    Chronic wounds are among the serious injuries which have called the attention of scientists to invest in an effort to fabricate temporary skin grafts and wound dressing materials. One of the widely acceptable solutions to this obstacle is to design a bioactive scaffold capable of regenerating tissue as well as delivering active agents to the site specific area. To this end, natural biopolymers are considered as suitable candidates to be employed in regenerative medicine due to their excellent biocompatibility. In addition, nanoparticles possess special properties such as the ability in sequestering the drug release which make them promising candidates in the fabrication of the... 

    Fabrication and Characterization of Hybrid NanoComposites Based on Epoxy/NanoDiamond/CarbonFiber

    , M.Sc. Thesis Sharif University of Technology Sepehri Sadeghian, Mohammad Sajjad (Author) ;
    Abstract
    Polymer composites, due to its exclusive properties, has a special place in industry. Epoxy resin with high adhesion property, low density, thermal stability and high chemical resistance has a special place as matrix in fabrication of high technology hybrid composites. Hybrid composites, due to its high strength and long fatigue life, used to reinforcing building structures and manufacturing fuselage. Layer and reactive structure near the firm core and wear-resistant of NDs, used to improvement of epoxy reisn and hybrid NanoComposite interphase properties. In this study, for improvement of the properties of hybrid NanoComposites, used the NDs in 0.25, 0.5 and 1 %wt with amine and carboxyl... 

    The Fabrication of Porous Scaffolds of Polyvinyl Chloride/Polyethylene Glycol and Nano Diamonds Using Gamma Radiation for Medical Applications

    , M.Sc. Thesis Sharif University of Technology Jabbar, Ali (Author) ; Frounchi, Masoud (Supervisor) ; Dadbin, Susan (Supervisor)
    Abstract
    Today, tissue engineering research is expanding to a large extent, so tissue engineering has the ability to build artificial organs and tissues. In this project, we have used two polymers of polyethylene glycol and polyvinyl chloride, which are used for network irradiation. After irradiation, these polymers were made by drying the freewheeling porous scaffolds and the effect of different parameters on the structure of these scaffolds was investigated. To investigate the effect of different factors on gelation, swelling, tensile test, degradability and finally the conditions of fibroplast cell growth on scaffolds were investigated. The results of the gel test showed that the gel was higher... 

    Preparation and Structure­properties Relationship in Rubber Toughened PA6 Reinforced with Nanodiamond

    , M.Sc. Thesis Sharif University of Technology Roosta, Reza (Author) ; Shojaei, Akbar (Supervisor)
    Abstract
    Polyamide6 has many engineering applications due to its physical, mechanical and processability properties. However, its low impact resistance limits the use of polyamide6. One of the common ways to overcome this problem and extend the range of polyamide6 application is its elasticity with elastomeric materials, which reduces the strength and modulus (tensile and flexure) in comparision with neat polyamide6. To overcome this limitation, various reinforcements, often fiber or particle-shaped, are used. Today, with the development of nanoparticles, this effort is being made to use nanoparticles, especially carbon nanoparticles with unique properties. Recent research has shown that the addition... 

    Mechanical, rheological and oxygen barrier properties of ethylene vinyl acetate/diamond nanocomposites for packaging applications

    , Article Diamond and Related Materials ; Volume 99 , 2019 ; 09259635 (ISSN) Amini, M ; Ramazani S. A., A ; Haddadi, S. A ; Kheradmand, A ; Sharif University of Technology
    Elsevier Ltd  2019
    Abstract
    In this work, the effects of the surface-modified nanodiamond particles (NDs) on the barrier, rheological, mechanical and thermal properties of ethylene vinyl acetate (EVA) composites for the packaging applications were investigated. Fourier transform infrared spectroscopy, as well as thermal gravimetric analysis were employed to study the grafting of vinyltriethoxy silane (VTS) on the surface of NDs. Afterwards, EVA samples containing 0, 0.1, 0.5, 1, 1.5 and 2 wt% of surface-modified NDs were prepared by a two-stage process including the solution and injection processes. In order to evaluate the physicochemical, rheological, mechanical and thermal properties of the EVA/NDs samples, field...