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Identifying brain functional connectivity alterations during different stages of alzheimer’s disease, Article International Journal of Neuroscience ; 2020 ; Fatemizadeh, E ; Motie-Nasrabadi, A ; Sharif University of Technology
Taylor and Francis Ltd 2020
Purpose: Alzheimer's disease (AD) starts years before its signs and symptoms including the dementia become apparent. Diagnosis of the AD in the early stages is important to reduce the speed of brain decline. Aim of the study: Identifying the alterations in the functional connectivity of the brain during the disease stages is among the main important issues in this regard. Therefore, in this study, the changes in the functional connectivity during the AD stages were analyzed. Materials and methods: By employing the functional magnetic resonance imaging (fMRI) data and graph theory, weighted undirected graphs of the whole-brain and default mode network (DMN) network were investigated...