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Article ACS Chemical Neuroscience ; Volume 12, Issue 17 , 2021 , Pages 3157-3166 ; 19487193 (ISSN) ; Bigdeli, A ; Hormozi Nezhad, M. R ; Sharif University of Technology
American Chemical Society 2021
The importance of tracing dopaminergic agents in the progression assessment of Parkinson's disease has boosted the demand for fast, sensitive, and real-time multi-analyte detection. Herein, visual and fingerprint fluorimetric patterns have been created by an optical sensor array to simultaneously detect and discriminate among levodopa, carbidopa, benserazide, and entacapone, as important dopaminergic agents. A dual emissive nanoprobe consisting of red quantum dots and blue carbon dots with an overall pink emission has been fabricated to provide unique emission patterns in the presence of the target analytes. The sensor elements in the array come from it's differential response in the absence...