Loading...
Search for:
electrochemical-dna-biosensors
0.01 seconds
A simple label-free electrochemical DNA biosensor based on carbon nanotube-DNA interaction
, Article RSC Advances ; Volume 6, Issue 19 , 2016 , Pages 15592-15598 ; 20462069 (ISSN) ; Salimian, R ; Kalhor, H. R ; Sharif University of Technology
Royal Society of Chemistry
2016
Abstract
A simple platform based on a hairpin oligonucleotide switch and multi-walled carbon nanotubes (MWCNTs) for the ultrasensitive detection of specific DNA sequences has been developed. In this approach, the π-stacking interaction of single-strand DNA-MWCNT was employed to construct an electrochemical DNA biosensor. Changes to the surface conductivity, based on the MWCNT replacement, were monitored by using the electrochemical species [Fe(CN)6]3-/4- as a redox probe. Morphological and voltammetric characterizations of the electrode surface were performed using atomic force microscopy (AFM), energy dispersive spectroscopy (EDS), cyclic voltammetry (CV), differential pulse voltammetry (DPV) and...