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    Design, Construction and Application of Nanostructured Electrochemical Biosensor Based on Aptamers for Diagnosis Some of the Pathogenic Bacteria

    , Ph.D. Dissertation Sharif University of Technology Ranjbar, Saba (Author) ; Shahrokhian, Saeed (Supervisor)
    Since that pathogenic bacteria have a predominant role in different aspects of human life such as clinical analysis and spread of contagious disease, food quality control and monitoring of environmental microbial infections, the aim of these studies is design and construction of electrochemical and electro-optical biosensors based on nanomaterials employing specific aptamer and antibody for detection of different bacteria in various real samples. An impedimetric biosensor based on nanoporous gold (NPG) was presented in the first part of the thesis for detection of Salmonella typhimurium as one of the main food- borne pathogenic bacterium. Three-dimensional structure of NPG was synthesized...