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    Experimental design in analytical chemistry - Part II: Applications

    , Article Journal of AOAC International ; Vol. 97, issue. 1 , 2014 , p. 12-18 Ebrahimi-Najafabadi, H ; Leardi, R ; Jalali-Heravi, M ; Sharif University of Technology
    Abstract
    This paper reviews the applications of experimental design to optimize some analytical chemistry techniques such as extraction, chromatography separation, capillary electrophoresis, spectroscopy, and electroanalytical methods  

    Artificial neural network modeling of peptide mobility and peptide mapping in capillary zone electrophoresis

    , Article Journal of Chromatography A ; Volume 1096, Issue 1-2 , 2005 , Pages 58-68 ; 00219673 (ISSN) Jalali Heravi, M ; Shen, Y ; Hassanisadi, M ; Khaledi, M. G ; Sharif University of Technology
    2005
    Abstract
    Recently, we have developed an artificial neural network model, which was able to predict accurately the electrophoretic mobilities of relatively small peptides. To examine the robustness of this methodology, a 3-3-1 back-propagation artificial neural network (BP-ANN) model was developed using the same inputs as the previous model, which were the Offord's charge over mass term (Q/M2/3), corrected steric substituent constant (E s,c) and molar refractivity (MR). The data set consisted of 102 peptides with a larger range of size than that of our earlier report - up to 42 amino acid residues as compared to 13 amino acids in the initial study - that also included highly charged and hydrophobic...