Sharif Digital Repository

The aim of this work was to synthesize hollow polyaniline nanostructures to be used as pH responsive nanoreservoirs for corrosion inhibitors in self-healing cotings. First, homogeneous and fairly monosized microspherers of polyaniline with nanosized shell was synthesized using a simple soft template method with β-naphthalene sulfonic acid (β-NSA) as both the surfactant and dopant, and ammonium persulfate (APS) as the oxidant at 2-5◦C. The morphology of PANI-NSA was successfully controlled from nanotubes to microsphere, by changing the synthesis conditions (i.e. pH, the concentration of surfactant and monomer, temperature, etc). Then, the nanostructured hollow PANI microspheres were applied... 

Propolis is a resin compound which is collected from different Plant sources by bees. It is processed by salivary enzymes and is combined with wax bee and is used in hives, Specially in entrance door. In this study Propolis is selected as a natural substance. The aim of this study is to change the substance to get use of in industry. For this, first, antimicrobial properties of it was proved and then for industrial use encapsulation was done to keep the capability of it. Since propolis extract was prepared with 70% ethanol, and the encapsulation was done with the polymer-effective material ratio of 5,0,1,2 by a proper polymer with no bad effect on the body. Later an appropriate powder was... 

Today, in order to increase the effectiveness of the drug and reduce its side effects, modern drug delivery systems replace the traditional methods of drug production. Some of these systems are designed to allow their drug release to proceed gradually and prolonged, so that its concentration in the blood remains at a relatively constant level and preserves the therapeutic effect of the drug. Aspirin or acetylsalicylic acid is a non-steroidal anti-inflammatory drug (NSAIDs). Aspirin is widely used to prevent secondary heart attacks and stroke and reduce the risk of death in patients with chronic coronary artery disease and stroke. Aspirin is used as an anticoagulant agent for patients with... 

Myocardial infarction (MI) is one of the diseases caused by the temporary or permanent cramp of major coronary arteries. Due to this blockage, blood flow to the heart's myocardial tissue is greatly reduced and finally the person suffered from a Heart stroke (HS). Heart tissue engineering is a promising approach, based on the combination of cells and suitable biomaterials to develop and create heart-like biological substitutes. Since high cardiac cell density, providing metabolic needs like oxygen and nutrients was a challenge. So creation of blood vessel networks within this type of designed tissue has been considered very much.The purpose of this project is to construct scaffolds with... 

This study aimed to prepare a type of microcapsule that microencapsulates folic acid and iron at the same time and protects these two substances against environmental and gastrointestinal conditions. Simultaneous release of these two nutrients has dual health properties and improves the efficiency of folic acid microencapsulation. In this study, biocomposites were formed containing alginate, pectin, and carboxymethylcellulose, and the microcapsules were synthesized by the ionization of calcium-alginate ions. Biocomposite optimization mixture with 13 experiments using experimental design software, optimal combination design method based on repopulation separator, restoring folic acid... 

Type 1 diabetes, formerly known as insulin-dependent diabetes, may present at any age, but is the most common type of diabetes affecting children and adolescents. People with type 1 diabetes do not produce enough insulin. This type accounts for 5-10% of all types of diabetes. In this type of diabetes, beta cell destruction occurs in the pancreas. In type 1 diabetes, the pancreas does not secrete any insulin; insulin is a hormone that enables the body to convert glucose in food into energy. If sugar in the blood cannot enter the cells, it accumulates in the arteries and results in high blood sugar. High blood sugar over time can have irreversible effects on various parts of the body. Curcumin... 

Beta cells are responsible for secreting insulin to maintain normoglycaemia throughout the individual’s life. Type 1 Diabetes Mellitus (T1DM) is a metabolic disorder characterized by an autoimmune response that promotes the destruction of beta-cells within the pancreatic islets, resulting in lifelong inadequate insulin secretion. Encapsulating beta cells inside a semipermeable membrane to protect encapsulated cells from direct contact with the host immune system, is a new way to treat type 1 diabetes without the need for long-term immunosuppression. . In this case, the semipermeable membrane surrounds the cells and allows oxygen, nutrients, and cell products to penetrate bilaterally while...