Sharif Digital Repository

Here we report a versatile new method for endfunctionalizing polystyrene. In order to produce polystyrene with an amino end group, 2-(3-bromo-3- phenylpropyl) isoindoline-1,3-dione was synthesized and used as a novel initiator for ATRP. After ATRP polymerization, tri-n-butyltin hydride ((n-Bu) 3SnH) reductively replace existing halogens on polymer chains by hydrogen. Finally, the phthaloyl groups on polymer backbone were cleaved by treatment with hydrazine yielding amino terminated polystyrene. A polymer with M n≈10,350 and M w/M n01.17 was obtained. Therefore, this method allows the preparation of amino end functionalized polystyrene of narrow polydispersity with complete degree of... 

With the high rate of mortality associated with breast cancer among women, breast cancer treatment has attracted great deal of attention globally. To reduce the exposure of body organs to high cytotoxicity of the common chemotherapeutic drugs, local co-delivery of selected chemotherapeutics has emerged as a solution. In this work, an electrospun composite including a co-drug-loaded graphene oxide-based nanocarrier is fabricated for local anticancer applications. To increase dispersion and cellular uptake of graphene oxide (GO), first, the hydroxyl groups at the edges of GO are grafted by poly (epichlorohydrin) (PCH) to form GO-PCH. Then, the hydroxyl end groups of PCH are grafted (g) with... 

We report a density functional non-equilibrium Green's function study of electrical transport in a single molecular conductor consisting of an ethane-dithiolate (C2H4S2) molecular wire with two sulfur end groups bonded to the Au(1 1 1) electrodes. We show that the current was increased by increasing the external voltage biases. The projected density of states (PDOS) and transmission coefficients T(E) under various external voltage biases are analyzed, and it suggests that the variation of the coupling between the molecule and the electrodes with external bias leads to the increase of the current. Furthermore, the investigation of the transport properties of the pentane-dithiolate (C5H10S2)...