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epileptic-rats
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Analysis of Epileptic Rats' EEG and Detection and Prediction of Epileptic Seizures
, M.Sc. Thesis Sharif University of Technology ; Vosoughi Vahdat, Bijan (Supervisor) ; Shamsollahi, Mohammad Bagher (Supervisor)
Abstract
Epilepsy is one of the most significant neurological disorders that about one percent of people suffer from it. Epilepsy can only be controlled, and so far no cure for it has been provided. Despite the many advances in the treatment of diseases, for a quarter of patients there is no medical treatment solution for controlling epileptic seizures. In the studies of medical groups on the epilepsy, one approach is employment of some models for each type of epilepsy. These types may be created in the animals to allow studying of the mechanism of epilepsy and also finding drugs of treatment or controlling seizures for each type of epilepsy. There is a type of epilepsy that is called absence...
A unified approach for detection of induced epileptic seizures in rats using ECoG signals
, Article Epilepsy and Behavior ; Volume 27, Issue 2 , 2013 , Pages 355-364 ; 15255050 (ISSN) ; Mousavi, S. R ; Motaghi, S ; Dehghani, A ; Vosoughi Vahdat, B ; Shamsollahi, M. B ; Sayyah, M ; Noorbakhsh, S. M ; Sharif University of Technology
2013
Abstract
Objective: Epileptic seizure detection is a key step for epilepsy assessment. In this work, using the pentylenetetrazole (PTZ) model, seizures were induced in rats, and ECoG signals in interictal, preictal, ictal, and postictal periods were recorded. The recorded ECoG signals were then analyzed to detect epileptic seizures in the epileptic rats. Methods: Two different approaches were considered in this work: thresholding and classification. In the thresholding approach, a feature is calculated in consecutive windows, and the resulted index is tracked over time and compared with a threshold. The moment the index crosses the threshold is considered as the moment of seizure onset. In the...